Risk factors of postoperative adhesive bowel obstruction in children with complicated appendicitis.

Autor: Feng W; Graduate School, Tianjin Medical University, Tianjin, 300070, China., Du XB; Department of Pediatric Surgery, Tianjin Children's Hospital, Tianjin, 300134, China., Zhao XF; Graduate School, Tianjin Medical University, Tianjin, 300070, China., Li MM; Department of Pediatric Surgery, Tianjin Children's Hospital, Tianjin, 300134, China., Cui HL; Department of Pediatric Surgery, Tianjin Children's Hospital, Tianjin, 300134, China. chlfjp@sina.com.
Jazyk: angličtina
Zdroj: Pediatric surgery international [Pediatr Surg Int] 2021 Jun; Vol. 37 (6), pp. 745-754. Date of Electronic Publication: 2021 Feb 04.
DOI: 10.1007/s00383-021-04862-w
Abstrakt: Purpose: Postoperative adhesive bowel obstruction (ABO) is a common complication especially in complicated appendicitis. This study aimed to analyze the risk factors for ABO following appendectomy in children with complicated appendicitis, and establish a scoring model for predicting postoperative ABO and treatment option to relieve the obstruction.
Methods: From December 2014 to January 2020, all files of consecutive patients with complicated appendicitis underwent appendectomy were reviewed. Univariate and multivariate analyses were used to screen out the risk factors of postoperative ABO, and establish a scoring model for predicting postoperative ABO and surgical relief to relieve the obstruction.
Results: Of the 780 patients, 87 (11.2%) had ABO following appendectomy, including 27 who underwent surgical relief. Age ≤ 6 years, overweight and obesity, duration of symptoms ≥ 36 h, C-reactive protein ≥ 99 mg/L, duration of operation ≥ 60 min, intraoperative peritoneal lavage, and postoperative flatus time ≥ 20 h were independent risk factors for postoperative ABO. The final scoring model for postoperative ABO included factors above, and exhibited a high degree of discrimination (area under the curve [AUC]: 0.937; 95% confidence interval [CI] 0.913-0.960) corresponding to an optimal cut-off value of 6: 82.8% sensitivity, 92.6% specificity. Furthermore, the scoring model showed a sensitivity of 74.1% and a specificity of 91.7% for patients wo underwent surgical relief to relieve obstruction with the optimal cut-off value of 9.
Conclusion: Risk factors for postoperative ABO should be taken seriously in children with complicated appendicitis. The scoring model is a novel but promising method to predict postoperative ABO and provide reference for clinical decision-making to relieve the obstruction.
Databáze: MEDLINE
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