Effects of Essential Oils-Based Supplement and Salmonella Infection on Gene Expression, Blood Parameters, Cecal Microbiome, and Egg Production in Laying Hens.

Autor: Laptev GY; BIOTROF+ Ltd., 8 Malinovskaya St, liter A, 7-N, Pushkin, 196602 St Petersburg, Russia., Yildirim EA; BIOTROF+ Ltd., 8 Malinovskaya St, liter A, 7-N, Pushkin, 196602 St Petersburg, Russia., Ilina LA; BIOTROF+ Ltd., 8 Malinovskaya St, liter A, 7-N, Pushkin, 196602 St Petersburg, Russia., Filippova VA; BIOTROF+ Ltd., 8 Malinovskaya St, liter A, 7-N, Pushkin, 196602 St Petersburg, Russia., Kochish II; K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology, 23 Akademika Skryabina St, 109472 Moscow, Russia., Gorfunkel EP; BIOTROF+ Ltd., 8 Malinovskaya St, liter A, 7-N, Pushkin, 196602 St Petersburg, Russia., Dubrovin AV; BIOTROF+ Ltd., 8 Malinovskaya St, liter A, 7-N, Pushkin, 196602 St Petersburg, Russia., Brazhnik EA; BIOTROF+ Ltd., 8 Malinovskaya St, liter A, 7-N, Pushkin, 196602 St Petersburg, Russia., Narushin VG; Research Institute for Environment Treatment, 69032 Zaporozhye, Ukraine.; Vita-Market Ltd., Yuzhnoye Shosse 1, 69032 Zaporozhye, Ukraine., Novikova NI; BIOTROF+ Ltd., 8 Malinovskaya St, liter A, 7-N, Pushkin, 196602 St Petersburg, Russia., Novikova OB; All-Russian Veterinary Research Institute of Poultry Science-Branch of the Federal State Budget Scientific Institution Federal Scientific Centre 'All-Russian Poultry Research and Technological Institute' of the Russian Academy of Sciences, 48 Chernikova St, Lomonosov, 198412 St Petersburg, Russia., Dunyashev TP; BIOTROF+ Ltd., 8 Malinovskaya St, liter A, 7-N, Pushkin, 196602 St Petersburg, Russia., Smolensky VI; K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology, 23 Akademika Skryabina St, 109472 Moscow, Russia., Surai PF; K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology, 23 Akademika Skryabina St, 109472 Moscow, Russia.; Department of Microbiology and Biochemistry, Faculty of Veterinary Medicine, Trakia University, 6000 Stara Zagora, Bulgaria.; Department of Animal Nutrition, Faculty of Agricultural and Environmental Sciences, Szent Istvan University, H-2103 Gödöllo, Hungary., Griffin DK; School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK., Romanov MN; K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology, 23 Akademika Skryabina St, 109472 Moscow, Russia.; School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.
Jazyk: angličtina
Zdroj: Animals : an open access journal from MDPI [Animals (Basel)] 2021 Feb 01; Vol. 11 (2). Date of Electronic Publication: 2021 Feb 01.
DOI: 10.3390/ani11020360
Abstrakt: One of the main roles in poultry resistance to infections caused by Salmonella is attributed to host immunity and intestinal microbiota. We conducted an experiment that involved challenging Lohmann White laying hens with Salmonella Enteritidis (SE), feeding them a diet supplemented with an EOs-based phytobiotic Intebio ® . At 1 and 7 days post-inoculation, the expression profiles of eight genes related to immunity, transport of nutrients in the intestine, and metabolism were examined. Cecal microbiome composition and blood biochemical/immunological indices were also explored and egg production traits recorded. As a result, the SE challenge of laying hens and Intebio ® administration had either a suppressive or activating effect on the expression level of the studied genes (e.g., IL6 and BPIFB3 ), the latter echoing mammalian/human tissue-specific expression. There were also effects of the pathogen challenge and phytobiotic intake on the cecal microbiome profiles and blood biochemical/immunological parameters, including those reflecting the activity of the birds' immune systems (e.g., serum bactericidal activity, β-lysine content, and immunoglobulin levels). Significant differences between control and experimental subgroups in egg performance traits (i.e., egg weight/number/mass) were also found. The phytobiotic administration suggested a positive effect on the welfare and productivity of poultry.
Databáze: MEDLINE
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