Atmospheric Occurrence of Organochlorine Pesticides and Inhalation Cancer Risk in Urban Areas at Southeast Brazil.

Autor: Guida Y; Laboratório de Micropoluentes Jan Japenga, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil; Laboratório de Radioisótopos Eduardo Penna Franca, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil. Electronic address: guidays@biof.ufrj.br., Carvalho GO; Laboratório de Radioisótopos Eduardo Penna Franca, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil., Capella R; Laboratório de Micropoluentes Jan Japenga, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil; Laboratório de Radioisótopos Eduardo Penna Franca, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil., Pozo K; RECETOX, Research Centre for Toxic Compounds in the Environment, Masaryk University, Kamenice 753/5, 625 00, Brno, Czech Republic; Facultad de Ingeniería y Tecnología, Universidad San Sebastián, Lientur, 1457, Concepción, Bío Bío, Chile., Lino AS; Laboratório de Radioisótopos Eduardo Penna Franca, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil., Azeredo A; Laboratório de Radioisótopos Eduardo Penna Franca, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil; Laboratório de Toxicologia, Instituto de Estudos Em Saúde Coletiva Universidade Federal Do Rio de Janeiro, Av. Horácio Macedo, 21941-598, Rio de Janeiro, RJ, Brazil., Carvalho DFP; Laboratório de Radioisótopos Eduardo Penna Franca, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil; Curso de Ciências Biológicas, Instituto de Ciências da Saúde, Universidade Paulista, Avenida Francisco Manoel, S/N, 11075-110, Santos, SP, Brazil., Braga ALF; Grupo de Avaliação de Exposição e Risco Ambiental, Programa de Pós-graduação Em Saúde Coletiva, Universidade Católica de Santos, Avenida Conselheiro Nébias, 300, 11015-002, Santos, SP, Brazil., Torres JPM; Laboratório de Micropoluentes Jan Japenga, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil., Meire RO; Laboratório de Micropoluentes Jan Japenga, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil; Laboratório de Radioisótopos Eduardo Penna Franca, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal Do Rio de Janeiro, Av. Carlos Chagas Filho, 373, 21941-902, Rio de Janeiro, RJ, Brazil.
Jazyk: angličtina
Zdroj: Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2021 Feb 15; Vol. 271, pp. 116359. Date of Electronic Publication: 2020 Dec 23.
DOI: 10.1016/j.envpol.2020.116359
Abstrakt: Organochlorine pesticides (OCPs) have been produced for almost a century and some of them are still used, even after they have been proved to be toxic, persistent, bioaccumulative and prone to long-range transport. Brazil has used and produced pesticides in industrial scales for both agricultural and public health purposes. Urban and industrial regions are of special concern due to their high population density and their increased exposure to chemical pollution, many times enhanced by chemical production, application or irregular dumping. Therefore, we aimed to investigate the occurrence of OCPs in outdoor air of urban sites from two major regions of southeast Brazil. Some of these sites have been affected by OCP production and their irregular dumping. Deterministic and probabilistic inhalation cancer risk (CR) assessments were conducted for the human populations exposed to OCPs in ambient air. Ambient air was mainly affected by Ʃ-HCH (median = 340 pg m -3 ) and Ʃ-DDT (median = 233 pg m -3 ), the only two OCPs registered for domissanitary purposes in Brazil. OCP concentrations tended to be higher in summer than in winter. Dumping sites resulted in the highest OCP atmospheric concentrations and, thus, in the highest CR estimations. Despite of all limitations, probabilistic simulations suggested that people living in the studied regions are exposed to an increased risk of hepatic cancer. Infants and toddlers (0 < 2 y) were exposed to the highest inhalation CRs compared to other age groups. Other exposure pathways (such as ingestion and dermic uptake) are needed for a more comprehensive risk assessment. Moreover, this study also highlights the need to review the human exposure to OCPs through inhalation and their respective CR in other impacted areas worldwide, especially where high levels of OCPs are still being measured.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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