Challenges of using protein antibiotics for pathogen control.

Autor: Chai R; College of Medical, Veterinary & Life Sciences, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, UK., Rooney WM; College of Medical, Veterinary & Life Sciences, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, UK.; Plant Science Group, College of Molecular, Veterinary & Life Sciences, University of Glasgow, Glasgow, UK., Milner JJ; Plant Science Group, College of Molecular, Veterinary & Life Sciences, University of Glasgow, Glasgow, UK., Walker D; College of Medical, Veterinary & Life Sciences, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, UK.
Jazyk: angličtina
Zdroj: Pest management science [Pest Manag Sci] 2021 Sep; Vol. 77 (9), pp. 3836-3840. Date of Electronic Publication: 2021 Feb 26.
DOI: 10.1002/ps.6312
Abstrakt: Bacterial phytopathogens represent a significant threat to many economically important crops. Current control measures often inflict harm on the environment and may ultimately impact on human health through the spread of antibiotic resistance. Antimicrobial proteins such as bacteriocins have been suggested as the next generation of disease control agents since they are able to specifically target the pathogen of interest with minimal impact on the wider microbial community and environment. However, substantial gaps in knowledge with regards to the efficacy and application of bacteriocins to combat phytopathogenic bacteria remain. Here we highlight the immediate challenges the community must address to ensure maximum exploitation of antimicrobial proteins in the field. © 2021 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
(© 2021 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.)
Databáze: MEDLINE
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