Disaggregated mortality from gastrointestinal cancers in Asian Americans: Analysis of United States death records.

Autor:	Huang RJ; Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, USA.; Stanford Center for Asian Health Research and Education (CARE), Stanford University School of Medicine, Stanford, California, USA., Sharp N; Stanford Center for Asian Health Research and Education (CARE), Stanford University School of Medicine, Stanford, California, USA., Talamoa R; Stanford Center for Asian Health Research and Education (CARE), Stanford University School of Medicine, Stanford, California, USA., Kapphahn K; Quantitative Science Unit, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Sathye V; Division of Hematology and Oncology, Stanford University School of Medicine, Stanford, California, USA., Lin B; Stanford Center for Asian Health Research and Education (CARE), Stanford University School of Medicine, Stanford, California, USA.; Division of Primary Care and Population Health, Stanford University School of Medicine, Stanford, California, USA., Srinivasan M; Stanford Center for Asian Health Research and Education (CARE), Stanford University School of Medicine, Stanford, California, USA.; Division of Primary Care and Population Health, Stanford University School of Medicine, Stanford, California, USA., Palaniappan LP; Stanford Center for Asian Health Research and Education (CARE), Stanford University School of Medicine, Stanford, California, USA.; Division of Primary Care and Population Health, Stanford University School of Medicine, Stanford, California, USA.
Jazyk:	angličtina
Zdroj:	International journal of cancer [Int J Cancer] 2021 Jun 15; Vol. 148 (12), pp. 2954-2963. Date of Electronic Publication: 2021 Feb 09.
DOI:	10.1002/ijc.33490
Abstrakt:	Asian Americans (AAs) are heterogeneous, and aggregation of diverse AA populations in national reporting may mask high-risk groups. Gastrointestinal (GI) cancers constitute one-third of global cancer mortality, and an improved understanding of GI cancer mortality by disaggregated AA subgroups may inform future primary and secondary prevention strategies. Using national mortality records from the United States from 2003 to 2017, we report age-standardized mortality rates, standardized mortality ratios and annual percent change trends from GI cancers (esophageal, gastric, colorectal, liver and pancreatic) for the six largest AA subgroups (Asian Indians, Chinese, Filipinos, Japanese, Koreans and Vietnamese). Non-Hispanic Whites (NHWs) are used as the reference population. We found that mortality from GI cancers demonstrated nearly 3-fold difference between the highest (Koreans, 61 per 100 000 person-years) and lowest (Asian Indians, 21 per 100 000 person-years) subgroups. The distribution of GI cancer mortality demonstrates high variability between subgroups, with Korean Americans demonstrating high mortality from gastric cancer (16 per 100 000), and Vietnamese Americans demonstrating high mortality from liver cancer (19 per 100 000). Divergent temporal trends emerged, such as increasing liver cancer burden in Vietnamese Americans, which exacerbated existing mortality differences. There exist striking differences in the mortality burden of GI cancers by disaggregated AA subgroups. These data highlight the need for disaggregated data reporting, and the importance of race-specific and personalized strategies of screening and prevention. (© 2021 UICC.)
Databáze:	MEDLINE
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