Resolution of Pseudophakic Cystoid Macular Edema: 2 mg Intravitreal Triamcinolone Acetonide versus 40 mg Posterior Sub-Tenon Triamcinolone Acetonide.

Autor:	Kuley B; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Storey PP; Austin Retina, University of Texas Dell Medical School, Austin, TX, USA., Wibbelsman TD; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Pancholy M; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Zhang QE; Biostatistics Consulting Core, Vickie and Jack Farber Vision Research Center, Wills Eye Hospital, Philadelphia, PA, USA., Sharpe J; Biostatistics Consulting Core, Vickie and Jack Farber Vision Research Center, Wills Eye Hospital, Philadelphia, PA, USA., Bello N; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Obeid A; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Regillo C; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Kaiser RS; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Chiang A; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Fineman MS; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Vander JF; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Gupta OP, Spirn MJ; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Dunn JP; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Mehta S; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Park CH; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Maguire JI; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA., Garg S; Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, PA, USA.
Jazyk:	angličtina
Zdroj:	Current eye research [Curr Eye Res] 2021 Jun; Vol. 46 (6), pp. 824-830. Date of Electronic Publication: 2021 Jan 31.
DOI:	10.1080/02713683.2020.1842458
Abstrakt:	Purpose: To compare 2 mg intravitreal triamcinolone (IVT) versus 40 mg posterior sub-Tenon triamcinolone acetonide (STT) for the treatment of eyes with pseudophakic cystoid macular edema. Methods: A retrospective, single-center review of eyes receiving 2 mg IVT between 3/1/2012-3/1/2017 and 40 mg STT between 1/1/2015-3/1/2017. Visual acuity (VA) and central macular thickness (CMT) were recorded at baseline, 1-, 3-, and 6-month follow-up visits. Results: Forty-five eyes were included in the IVT group and 50 eyes in the STT group. Change in VA from baseline to 1, 3, and 6 months was not significantly different between IVT and STT (6 months: 2.3 lines vs. 2.4 lines, p = .10). The IVT group achieved significantly better CMT improvement from baseline compared to STT at 1 month (255 μm vs. 187 μm; p = .03), but this difference was not present at month 3 (214 μm vs. 212 μm; p = .79) or month 6 (176 μm vs. 207 μm; p = .29). During the 6-month follow-up period, approximately 7% of eyes in the IVT group and 12% of eyes in the STT group developed ocular hypertension ( p = .43), and all cases were successfully managed with topical anti-ocular hypertensive therapy or observation. Conclusions: 2 mg IVT and 40 mg STT both achieved significant improvement in vision and CMT with no significant difference between interventions at 3- and 6-month follow-up.
Databáze:	MEDLINE
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