Disseminated and ulcerative basidiobolomycosis simulating a Buruli ulcer in an immunocompetent girl in Southern Benin.

Autor:	Habib A; Centre de Dépistage et de Traitement de la Lèpre et de l´Ulcère de Buruli de Pobè, Fondation Raoul Follereau, Cotonou, Bénin., D Almeida C; Service de Dermatologie-Vénérologie, Hôpital d´Instruction des Armées de Cotonou, Cotonou, Bénin., Degboe B; Faculté des Sciences de la Santé, Université d´Abomey-Calavi, Cotonou, Bénin.; Service de Dermatologie-Vénérologie, Centre National Hospitalier et Universitaire Hubert Koutoukou Maga, Cotonou, Bénin., Morvant B; Département de Pathologie Cellulaire et Tissulaire, Unité de Formation d'Anatomie Cytologie Pathologique, Centre Hospitalier et Universitaire d´Angers, Angers, France., Ganlonon ML; Centre de Dépistage et de Traitement de la Lèpre et de l´Ulcère de Buruli de Pobè, Fondation Raoul Follereau, Cotonou, Bénin., Adeye A; Centre de Dépistage et de Traitement de la Lèpre et de l´Ulcère de Buruli de Pobè, Fondation Raoul Follereau, Cotonou, Bénin., Croue A; Département de Pathologie Cellulaire et Tissulaire, Unité de Formation d'Anatomie Cytologie Pathologique, Centre Hospitalier et Universitaire d´Angers, Angers, France., Kiki M; Centre de Dépistage et de Traitement de la Lèpre et de l´Ulcère de Buruli de Pobè, Fondation Raoul Follereau, Cotonou, Bénin., Sodjinou E; Centre de Dépistage et de Traitement de la Lèpre et de l´Ulcère de Buruli de Pobè, Fondation Raoul Follereau, Cotonou, Bénin.
Jazyk:	angličtina
Zdroj:	The Pan African medical journal [Pan Afr Med J] 2020 Nov 11; Vol. 37, pp. 227. Date of Electronic Publication: 2020 Nov 11 (Print Publication: 2020).
DOI:	10.11604/pamj.2020.37.227.20994
Abstrakt:	Basidiobolomycosis is a subcutaneous mycosis, for which non-specific clinical presentation can be a source of diagnostic wandering. A 5-year-old girl was brought for consultation with chronic ulcers of the pelvic limbs evolving for 8 months. The lesions started when the girl was 18 months old with a painless, pruritic nodule of the right buttock, indurated placard following progressive extension to the pelvic limbs, back and abdomen, and secondarily ulcerated in several places. On examination, there was an alteration of the general condition, a large, indurated and erythematous plaque, with sharp edges. On this plaque, there were nodular lesions and necrotic ulcers, with detached margins. The left knee was blocked in flexion. Ziehl staining and polymerase chain reaction for Mycobacterium ulcerans were negative. The histopathological picture was suggestive of basidiobolomycosis. The evolution was favorable after giving her ketoconazole (100mg per day) for 14 weeks associated with surgery and physiotherapy. This clinical case confirms the difficulties in diagnosing basidiobolomycosis, especially in endemic areas of Buruli ulcer. Competing Interests: The authors declare no competing interests. (Copyright: Akimath Habib et al.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu Plný text ve formátu PDF