| Autor: |
Lou SZ; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650031, China.; School of Chemistry and Environment, Yunnan Minzu University, Kunming 650031, China., Feng J; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650031, China., Yang R; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650031, China., Li YP; School of Chinese Pharmacy, Yunnan University of Chinese Medicine, Kunming 650500, China., Gao L; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650031, China., Du G; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650031, China., Yang HY; School of Chemistry and Environment, Yunnan Minzu University, Kunming 650031, China., Hu QF; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650031, China., Zhou WB; Yunnan Tobacco Company, Yuxi Branch, Yuxi 653100, China., Wang LS; College of Pharmacy, Guilin Medical University, Guilin 541199, China., Wang WG; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650031, China. |
| Abstrakt: |
Two new sesquiterpene aryl esters, armimelleolides A and B ( 1 and 2 ), and four known ones, were isolated from the EtOAc extract of Armillaria gallica 012 m by column chromatography on silica gel, reversed-phase C 18 silica gel and semi-preparative HPLC. Their structures were elucidated on the basis of spectroscopic methods, including extensive 1 D NMR, 2 D NMR and MS. All these compounds showed potential antitumor activities against at least one of the human cancer cell lines (A549, HCT-116, M231 and W256), with IC 50 ranging from 2.57 to 19.94 μM. |
