Impact of different patterns of metastasis in non-small-cell lung cancer patients.

Autor:	da Silva LM; Brazilian National Cancer Institute & Federal University of The State of Rio de Janeiro, Rio de Janeiro, 22290-240, Brazil., da Silva GT; Brazilian National Cancer Institute, Rio de Janeiro, 20231-092, Brazil., Bergmann A; Brazilian National Cancer Institute, Rio de Janeiro, 20231-092, Brazil., Costa GJ; Instituto de Medicina Integral Prof. Fernando Figueira & Hospital de Câncer de Pernambuco, Recife, Pernambuco, 41825-906, Brazil., Zamboni MM; Brazilian National Cancer Institute, Rio de Janeiro, 20231-092, Brazil., Santos Thuler LC; Brazilian National Cancer Institute & Federal University of The State of Rio de Janeiro, Rio de Janeiro, 22290-240, Brazil.
Jazyk:	angličtina
Zdroj:	Future oncology (London, England) [Future Oncol] 2021 Mar; Vol. 17 (7), pp. 775-782. Date of Electronic Publication: 2021 Jan 29.
DOI:	10.2217/fon-2020-0587
Abstrakt:	Aim: The aim of this study was to evaluate the frequency and median time for the development of metastases and prognosis by metastatic site after the diagnosis of non-small-cell lung cancer (NSCLC). Patients & methods: This cohort study was conducted with 1096 patients diagnosed with NSCLC between 2006 and 2014. Results: The most prevalent site of NSCLC metastases was the respiratory system. The nervous and adrenal systems presented the longest median time for the development of metastases. The 6-month survival varied from 68.2% for liver to 79.9% for the nervous system. Bone metastases were associated with a higher risk of death. Conclusion: The respiratory system was the most prevalent site of metastases. OS and risk of death varied according to the metastatic site.
Databáze:	MEDLINE
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