Primary amenorrhoea as a manifestation of coeliac disease.
| Autor: | Costa STB; Pediatrics - HVFX, José Mello Saude Group, CUF, Carnaxide, Portugal sara.tbferreiracosta@gmail.com.; Pediatrics, Santa Maria Hospital, Lisboa, Portugal., Sanmarful IS; Pediatrics - HVFX, José Mello Saude Group, CUF, Carnaxide, Portugal. |
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| Jazyk: | angličtina |
| Zdroj: | BMJ case reports [BMJ Case Rep] 2021 Jan 27; Vol. 14 (1). Date of Electronic Publication: 2021 Jan 27. |
| DOI: | 10.1136/bcr-2020-239260 |
| Abstrakt: | Coeliac disease is a systemic autoimmune disorder that has a wide range of clinical manifestations that include abdominal pain, diarrhoea, obstipation, weight loss, short stature and even primary amenorrhoea. It can be asymptomatic, which makes it an underdiagnosed disease. We present a case report of a 15-year-old girl who was referred to a paediatric consultation due to primary amenorrhoea. A detailed clinical history revealed poor weight gain. Physical examination showed that secondary sexual characteristics were present and there was a low body mass index. Ultrasonography images and laboratory tests revealed a normal urogenital system and an adequate gonadal function. Coeliac disease antibodies were positive and the diagnosis was confirmed through duodenal biopsy. The symptom resolved with a gluten-free diet. An approach to primary amenorrhoea should always include investigation of a systemic illness as it is a rare but treatable diagnosis. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.) |
| Databáze: | MEDLINE |
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