Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial.

Autor:	Moreno-Peral P; Primary Care District of Málaga-Guadalhorce, Instituto de Investigación Biomédica de Málaga-IBIMA, Primary Care Prevention and Health Promotion Network (redIAPP), Spain., Conejo-Cerón S; Primary Care District of Málaga-Guadalhorce, Instituto de Investigación Biomédica de Málaga-IBIMA, Primary Care Prevention and Health Promotion Network (redIAPP), Spain., de Dios Luna J; Department of Biostatistics, Medical School, University of Granada, Granada, Spain., King M; Mental Health Sciences, Faculty of Brain Sciences., Nazareth I; Department of Primary Care and Population Health, UCL, London, UK., Martín-Pérez C; Marquesado Health Centre, Northeast Area of Granada, Spain., Fernández-Alonso C; Service Assistance Programs, Regional Health Management Valladolid, Spain., Ballesta-Rodríguez MI; Federico del Castillo Health Centre, Jaén, Spain., Fernández A; Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Barcelona, Spain; CIBERESP, Centro de Investigacion Biomedica en Red de Epidemiologia y Salud Publica, Spain., Aiarzaguena JM; San Ignacio Health Centre, Primary Care Research Unit, Osakidetza Bilbao, Spain., Montón-Franco C; Casablanca Health Centre, Aragonese Institute of Health Sciences, IIS Aragón, Department of Medicine and Psychiatry, University of Zaragoza, Spain., Bellón JÁ; El Palo Health Centre, Andalusian Health Service (SAS); Primary Care District of Málaga-Guadalhorce; Biomedical Research Institute of Málaga (IBIMA); Primary Care Prevention and Health Promotion Network (redIAPP); Department of Public Health and Psychiatry, University of Málaga, Spain.
Jazyk:	angličtina
Zdroj:	The British journal of general practice : the journal of the Royal College of General Practitioners [Br J Gen Pract] 2021 Jan 28; Vol. 71 (703), pp. e95-e104. Date of Electronic Publication: 2021 Jan 28 (Print Publication: 2021).
DOI:	10.3399/bjgp20X714041
Abstrakt:	Background: In the predictD-intervention, GPs used a personalised biopsychosocial programme to prevent depression. This reduced the incidence of major depression by 21.0%, although the results were not statistically significant. Aim: To determine whether the predictD-intervention is effective at preventing anxiety in primary care patients without depression or anxiety. Design and Setting: Secondary study of a cluster randomised trial with practices randomly assigned to either the predictD-intervention or usual care. This study was conducted in seven Spanish cities from October 2010 to July 2012. Method: In each city, 10 practices and two GPs per practice, as well as four to six patients every recruiting day, were randomly selected until there were 26-27 eligible patients for each GP. The endpoint was cumulative incidence of anxiety as measured by the PRIME-MD screening tool over 18 months. Results: A total of 3326 patients without depression and 140 GPs from 70 practices consented and were eligible to participate; 328 of these patients were removed because they had an anxiety syndrome at baseline. Of the 2998 valid patients, 2597 (86.6%) were evaluated at the end of the study. At 18 months, 10.4% (95% CI = 8.7% to 12.1%) of the patients in the predictD-intervention group developed anxiety compared with 13.1% (95% CI = 11.4% to 14.8%) in the usual-care group (absolute difference = -2.7% [95% CI = -5.1% to -0.3%]; P = 0.029). Conclusion: A personalised intervention delivered by GPs for the prevention of depression provided a modest but statistically significant reduction in the incidence of anxiety. (© The Authors.)
Databáze:	MEDLINE
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