Lewis Acid Activation of Fragment-Coupling Reactions of Tertiary Carbon Radicals Promoted by Visible-Light Irradiation of EDA Complexes.

Autor: Pitre SP; Department of Chemistry, Oklahoma State University, 107 Physical Sciences, Stillwater, Oklahoma 74078, United States., Allred TK; Department of Chemistry, University of California, Irvine, California 92697-2025, United States., Overman LE; Department of Chemistry, University of California, Irvine, California 92697-2025, United States.
Jazyk: angličtina
Zdroj: Organic letters [Org Lett] 2021 Feb 05; Vol. 23 (3), pp. 1103-1106. Date of Electronic Publication: 2021 Jan 25.
DOI: 10.1021/acs.orglett.1c00023
Abstrakt: The addition of tertiary carbon radicals generated from N -(acyloxy)phthalimide esters to cyclic α,β-unsaturated ketones and lactones is markedly enhanced by the addition of substoichiometric amounts of a Ln(OTf) 3 . The reaction is accomplished by irradiation with visible light in the absence of a photosensitizer and is suggested to proceed by excitation of a ternary electron donor-acceptor complex between the NHPI ester, Hantzsch ester, and a Ln(OTf) 3 .
Databáze: MEDLINE
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