A qualitative study of antiretroviral therapy adherence interruptions among young Latino men who have sex with men with HIV: Project D.A.I.L.Y.

Autor: Sheehan DM; Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA.; Center for Substance Use and HIV/AIDS Research on Latinos in the United States (C-SALUD), Florida International University, Miami, FL, USA.; Research Centers in Minority Institutions (RCMI), Florida International University, Miami, FL, USA., De La Cruz Y; Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA., Ramírez-Ortiz D; Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA., Swendeman D; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Muñoz-Laboy M; Community Health and Social Medicine Department, The City College of New York, New York, NY, USA., Duncan DT; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Cano MÁ; Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA.; Center for Substance Use and HIV/AIDS Research on Latinos in the United States (C-SALUD), Florida International University, Miami, FL, USA., Devieux JG; Department of Health Promotion and Disease Prevention, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA., Trepka MJ; Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA.; Research Centers in Minority Institutions (RCMI), Florida International University, Miami, FL, USA.
Jazyk: angličtina
Zdroj: AIDS care [AIDS Care] 2021 Jul; Vol. 33 (7), pp. 962-969. Date of Electronic Publication: 2021 Jan 23.
DOI: 10.1080/09540121.2021.1874277
Abstrakt: Consistent antiretroviral therapy (ART) adherence is necessary for HIV viral suppression. However, adherence may fluctuate around daily routines and life events, warranting intervention support. We examined reasons for ART adherence interruptions, using in-depth, semi-structured qualitative interviews, among young (18-34-year-old) Latino men who have sex with men (YLMSM) with HIV. Interviews ( n  = 24) were guided by the Theory of Planned Behavior, the Information-Motivation-Behavioral Skills Theory, and the Socio-Ecological Model. Two coders independently coded transcripts using NVivo 12 software and synthesized codes into themes using Thematic Content Analysis. Results suggested 4 primary influences on ART adherence interruptions: (1) HIV diagnosis denial, (2) breaks in daily routine, (3) substance use, and (4) HIV status disclosure. Participant quotes highlighted routinization of pill-taking and planning ahead for breaks in routine as critically important. The narrative suggested modification of pill-taking routines during alcohol use, and that periods most vulnerable for long-term interruptions in ART adherence were following an HIV diagnosis and during periods of drug use. Support at the time of HIV diagnosis, including a plan for routinization of pill taking, and adaptive interventions incorporating real-time support during breaks in routines and substance use episodes may be one way to help YLMSM adhere to ARTs.
Databáze: MEDLINE