Evaluating CO 2 laser-assisted sclerectomy surgery with mitomycin C combined with or without phacoemulsification in adult Asian glaucoma subjects.
| Autor: | Ho DCW; Department of Ophthalmology, National Healthcare Group Eye Institute, Khoo Teck Puat Hospital, Yishun, Singapore., Perera SA; Singapore National Eye Centre, 11 Third Hospital Ave, Singapore, 168751, Singapore.; Singapore Eye Research Institute, 20 College Road Discovery Tower, Level 6 The Academia, Singapore, Singapore.; Duke-NUS Medical School, 8 College Road, Khoo Teck Puat Building, Singapore, Singapore., Hla MH; Singapore Eye Research Institute, 20 College Road Discovery Tower, Level 6 The Academia, Singapore, Singapore.; Duke-NUS Medical School, 8 College Road, Khoo Teck Puat Building, Singapore, Singapore., Ho CL; Singapore National Eye Centre, 11 Third Hospital Ave, Singapore, 168751, Singapore. ho.ching.lin@singhealth.com.sg.; Singapore Eye Research Institute, 20 College Road Discovery Tower, Level 6 The Academia, Singapore, Singapore. ho.ching.lin@singhealth.com.sg. |
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| Jazyk: | angličtina |
| Zdroj: | International ophthalmology [Int Ophthalmol] 2021 Apr; Vol. 41 (4), pp. 1445-1454. Date of Electronic Publication: 2021 Jan 22. |
| DOI: | 10.1007/s10792-021-01707-2 |
| Abstrakt: | Purpose: To evaluate and compare outcomes of CO Design: Retrospective, comparative study. Methods: Adult Asian glaucoma patients who underwent CLASS alone or combined with phacoemulsification using standardized surgery by two trained glaucoma surgeons between 2014 and 2016 were identified. The main measures of outcome were: intraocular pressure (IOP), use of supplemental medical therapy, best-corrected visual acuity (BCVA), microperforations, macroperforations, and repeated intervention(s) for glaucoma. Results: Forty-one eyes who underwent CLASS alone (13 eyes) or combined with phacoemulsification (28 eyes) were included. Overall, BCVA improved from 0.28 ± 0.19 to 0.14 ± 0.17, and 0.17 ± 0.19, 0.22 ± 0.24, and 0.18 ± 0.23 at 6, 12, 24, and 36 months, respectively. Mean IOP dropped from 17.9 ± 4.7 mmHg to 14.6 ± 5.5, 13.9 ± 3.3, 14.3 ± 3.6, and 14.1 ± 3.7 mmHg, and average number of medications reduced from 2.9 ± 0.9 to 0.2 ± 0.6, 0.5 ± 0.9, 1.0 ± 1.2, and 1.3 ± 1.4 at the same time points. There was no statistically significant difference in BCVA, IOP, and medication reduction between the two groups. Conclusions: CLASS combined with or without phacoemulsification was equally safe and effective, but yielded more modest results in our population. |
| Databáze: | MEDLINE |
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