Evaluation of the tear parameters of ovulation induction patients in a short time period with anterior segment optical coherence tomography.

Autor:	Çolak E; Obstetrics and Gynaecology Department, Faculty of Medicine, Baskent University, Konya, Turkey., Ulusoy MO; Ophthalmology Department, Faculty of Medicine, Baskent University, Konya, Turkey., Ceran MU; Obstetrics and Gynaecology Department, Faculty of Medicine, Baskent University, Konya, Turkey., Taşdemir Ü; Obstetrics and Gynaecology Department, Faculty of Medicine, Baskent University, Konya, Turkey., Kal A; Ophthalmology Department, Faculty of Medicine, Baskent University, Konya, Turkey., Özçimen EE; Obstetrics and Gynaecology Department, Faculty of Medicine, Baskent University, Konya, Turkey.
Jazyk:	angličtina
Zdroj:	Arquivos brasileiros de oftalmologia [Arq Bras Oftalmol] 2020 Nov-Dec; Vol. 83 (6), pp. 511-516.
DOI:	10.5935/0004-2749.20200095
Abstrakt:	Purpose: The effects of sex steroid hormones on tearparameters are known. Theaim of this studywas to examine the effects on tear parameters during exposure to high-dose sex steroids in a short period of time. Methods: Forty patients who were admitted to the infertility clinic of our hospital and planned to undergo ovulation induction with exogenous gonadotropins were included in our study. Prior tothe initiation of ovulation induction, the basal levels of estradiol were measured on day 3 of the menstrual cycle and ophthalmologic examinations were performed by the ophthalmology department of our hospital. The estradiol levels were-measured on the day ofovulation induction usinghuman chorionic gonadotropin and compared with basal estra-diol; eye examinations were also repeated. Result: Forty women with reproductive period and average age of 33.3 ± 4.2 years were included in this study. Basal levels of estradiol were significantly (p<0.001) higher after ovulation induction than before induction. The scores in the break-up timeand after induction were 6.2 ± 2.8 sn and 8.4 ± 1.4 sn, respectively. The values of Schirmer's test were 14.3 ± 7.1 mm and 20.6 ± 6.2 mm before and after induction, respectively. Both values were significantly higher after ovulation induction (p<0.001; p=0.001, respectively). Conclusion: We observed impro-vemet in tear function tests following the use of estradiol even for a limited time.The use of estradiol during menopause may improve dry eye symptoms in patients.
Databáze:	MEDLINE
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