Chemical Composition and Cytotoxic Evaluation of the Essential Oil of Phyllogonium viride (Phyllogoniaceae, Bryophyta).

Autor:	Klegin C; Programa de Pós-graduação em Ambiente e Sustentabilidade, Universidade Estadual do Rio Grande do Sul (UERGS) - Campus Hortênsias, Rua Assis Brasil, No. 842, Centro, CEP, 95400-000, São Francisco de Paula, RS, Brazil., de Moura NF; Universidade Federal do Rio Grande - Campus Santo Antônio da Patrulha (FURG/SAP), Rua Coronel Francisco Borges de Lima, 3005, Bairro Bom Princípio, CEP, 955900-000, Santo Antônio da Patrulha, RS, Brazil., Oliveira de Sousa MH; Universidade Federal do Rio Grande - Campus Santo Antônio da Patrulha (FURG/SAP), Rua Coronel Francisco Borges de Lima, 3005, Bairro Bom Princípio, CEP, 955900-000, Santo Antônio da Patrulha, RS, Brazil., Frassini R; Universidade de Caxias do Sul - Campus Sede, Rua Francisco Getúlio Vargas, 1130, Bairro Petrópolis, CEP, RS 95070-560, Caxias do Sul, Brazil., Roesch-Ely M; Universidade de Caxias do Sul - Campus Sede, Rua Francisco Getúlio Vargas, 1130, Bairro Petrópolis, CEP, RS 95070-560, Caxias do Sul, Brazil., Bruno AN; Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Sul - Campus Porto Alegre (IFRS/POA), Rua Cel. Vicente, 281, Bairro Centro Histórico, CEP, 90030-041, Porto Alegre, RS, Brazil., Bitencourt TC; Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Sul - Campus Porto Alegre (IFRS/POA), Rua Cel. Vicente, 281, Bairro Centro Histórico, CEP, 90030-041, Porto Alegre, RS, Brazil., Flach A; Universidade Federal de Roraima - Campus do Paricarana, Av. Cap. Enê Garcêz, 2413, Bloco III, Aeroporto, CEP, 69310-000, Paricarana, RR, Brazil., Bordin J; Programa de Pós-graduação em Ambiente e Sustentabilidade, Universidade Estadual do Rio Grande do Sul (UERGS) - Campus Hortênsias, Rua Assis Brasil, No. 842, Centro, CEP, 95400-000, São Francisco de Paula, RS, Brazil.; Universidade Estadual do Rio Grande do Sul - Campus Litoral Norte (UERGS/LN), Rua Machado de Assis, No. 1456, Sulbrasileiro, CEP, 95520-000, Osório, RS, Brazil.
Jazyk:	angličtina
Zdroj:	Chemistry & biodiversity [Chem Biodivers] 2021 Mar; Vol. 18 (3), pp. e2000794. Date of Electronic Publication: 2021 Feb 17.
DOI:	10.1002/cbdv.202000794
Abstrakt:	The present study aimed to determine the chemical composition and biological activity of the essential oil obtained from Phyllogonium viride Brid. (Phyllogoniaceae, Bryophyta), whose samples were collected in southern Brazil. For the first time, the cytotoxic activity of the essential oil of P. viride in breast and colorectal tumor cells (MCF-7 and HCT-116) was evaluated, as well as the cytotoxic potential of this oil in non-tumoral cells of human immortalized keratinocytes (HaCaT) via MTT assay. The compounds majorly found in P. viride essential oil were β-bazzanene (20.30 %), β-caryophyllene (17.06 %), β-chamigrene (14.02), and germacrene B (11.72 %). Treatment with P. viride essential oil in the different tested cell lines did not induce any toxicity in most of the tested concentrations. These data contribute to generating new scientific information about this understudied plant species. Furthermore, the chemical characterization of the compounds present in the essential oil of P. viride can lead to greater elucidation of its biotechnological potential. (© 2021 Wiley-VHCA AG, Zurich, Switzerland.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu Plný text