Tolosa-Hunt syndrome relapse during pregnancy following chronic intake of combined oral contraceptives.
| Autor: | Piamonte BLC; Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Metro Manila, Philippines bcpiamonte@gmail.com., Ong KL; Department of Obstetrics and Gynecology, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Metro Manila, Philippines., Cenina AR; Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Metro Manila, Philippines. |
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| Jazyk: | angličtina |
| Zdroj: | BMJ case reports [BMJ Case Rep] 2021 Jan 18; Vol. 14 (1). Date of Electronic Publication: 2021 Jan 18. |
| DOI: | 10.1136/bcr-2020-238944 |
| Abstrakt: | Tolosa-Hunt syndrome (THS) is a rare syndrome of painful ophthalmoplegia secondary to an idiopathic granulomatous inflammation affecting the cavernous sinus, superior orbital fissure or orbit. Pregnancy and pregnancy-related hormones have been identified as potential triggers. A 39-year-old gravida-2 para-1 woman with prior chronic intake of combined oral contraceptives (COC) suffered two episodes of painful ophthalmoplegia-the first event with spontaneous remission and the relapse occurring during pregnancy and with complete resolution following steroid treatment. MRI revealed a postinflammatory mass at the junction of the left orbital apex and anterior cavernous sinus, supporting the diagnosis of THS. To our knowledge, this is the first report of a THS relapse occurring during pregnancy following a chronic history of COC intake. This case adds to the growing evidence supporting the relationship between immune and hormonal factors that may be present during pregnancy and the disease pathogenesis of THS. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.) |
| Databáze: | MEDLINE |
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