Sulforaphane in broccoli: The green chemoprevention!! Role in cancer prevention and therapy.
Autor: | Nandini DB; Department of Oral Pathology and Microbiology, Dental College, Regional Institute of Medical Sciences, Imphal, Manipur, India., Rao RS; Department of Oral Pathology and Microbiology, M. S. Ramaiah Dental College, Bengaluru, Karnataka, India., Deepak BS; Department of Conservative Dentistry, Dental College, Regional Institute of Medical Sciences, Imphal, Manipur, India., Reddy PB; Department of Oral and Maxillofacial Surgery, Dental College, Regional Institute of Medical Sciences, Imphal, Manipur, India. |
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Jazyk: | angličtina |
Zdroj: | Journal of oral and maxillofacial pathology : JOMFP [J Oral Maxillofac Pathol] 2020 May-Aug; Vol. 24 (2), pp. 405. Date of Electronic Publication: 2020 Sep 09. |
DOI: | 10.4103/jomfp.JOMFP_126_19 |
Abstrakt: | Isothicyanates present in cruciferous vegetables are known to exhibit chemoprevention by various mechanisms. Presently, there is growing evidence that a phytochemical compound known as sulforaphane in these green leafy vegetables is found to be effective in preventing and treating various cancers such as prostate cancer, breast cancer, colon cancer, skin, urinary bladder and oral cancers. This component is naturally present in the broccoli sprouts, kale, cabbage, cauliflower and garden cress and is available as a commercial supplementary pill called Broccoli extract. Availability of many bioactive substances such as vitamins, polyphenols, sulfides, glucosinolates and antioxidants makes broccoli consumption important in daily diet regularly. Researchers have named it as "Green chemoprevention." It is easily affordable and more cost-effective than the traditional chemopreventive drugs. Results from the epidemiological and experimental studies have emphasized the role of sulforophane as a complementary or alternative chemopreventive agent. Competing Interests: There are no conflicts of interest. (Copyright: © 2020 Journal of Oral and Maxillofacial Pathology.) |
Databáze: | MEDLINE |
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