Atherogenic index of plasma as a marker of cardiovascular risk factors in Mexicans aged 18 to 22 years.
| Autor: | Kammar-García A; Department of Biochemistry, School of Medicine, Benemérita Universidad Autónoma de Puebla, Mexico.; Emergency Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, Mexico., López-Moreno P; Department of Biochemistry, School of Medicine, Benemérita Universidad Autónoma de Puebla, Mexico., Hernández-Hernández ME; Department of Biochemistry, School of Medicine, Benemérita Universidad Autónoma de Puebla, Mexico., Ortíz-Bueno AM; Department of Biochemistry, School of Medicine, Benemérita Universidad Autónoma de Puebla, Mexico., Martínez-Montaño MLC; Department of Biochemistry, School of Medicine, Benemérita Universidad Autónoma de Puebla, Mexico. |
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| Jazyk: | angličtina |
| Zdroj: | Proceedings (Baylor University. Medical Center) [Proc (Bayl Univ Med Cent)] 2020 Aug 21; Vol. 34 (1), pp. 22-27. Date of Electronic Publication: 2020 Aug 21. |
| DOI: | 10.1080/08998280.2020.1799479 |
| Abstrakt: | The aim of this cross-sectional study was to evaluate the use and application of the atherogenic index of plasma (AIP) in the prediction of cardiovascular risk factors including mixed hyperlipidemia, hypertension, hyperuricemia, and metabolic syndrome in a population of young Mexican adults. Values were obtained for metabolic parameters, such as glucose, triglycerides, cholesterol (total, high-density, low-density, and very low density), systolic and diastolic blood pressure, and uric acid. Through univariate and multivariate analysis, parametric comparisons were applied and receiver operating characteristic curves were plotted. Logistic regression analysis was used to assess the risk of hyperuricemia, hypertension, mixed hyperlipidemia, and metabolic syndrome from a high AIP. Metabolic parameters and AIP had a significant correlation, with higher rates observed with increased AIP. As a set, metabolic parameters increased with an AIP >0.21 (λ Wilks = 0.58, F(14,344) = 7.7, P < 0.0001). The area under the curve was statistically significant for prediction of hyperuricemia (0.6), mixed hyperlipidemia (0.9), hypertension (0.8), and metabolic syndrome (0.95). In conclusion, in a sample of young Mexican adults, AIP was strongly associated with cardiovascular risk factors and could serve as a useful marker for the prediction of metabolic alterations related to cardiovascular disease. (Copyright © 2020 Baylor University Medical Center.) |
| Databáze: | MEDLINE |
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