Granulomatosis With Polyangiitis in a Pediatric Male.
| Autor: | Saenz Rios F; Radiology, University of Texas Medical Branch, Galveston, USA., Devaraj S; Family Medicine, The University of Texas Health Science Center, Tyler, USA., Movva G; Radiology, University of Texas Medical Branch, Galveston, USA., Movva H; Medicine, University of Texas Rio Grande Valley School of Medicine, Edinburg, USA., Nguyen QD; Radiology, University of Texas Medical Branch, Galveston, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2020 Dec 13; Vol. 12 (12), pp. e12055. Date of Electronic Publication: 2020 Dec 13. |
| DOI: | 10.7759/cureus.12055 |
| Abstrakt: | Significant eosinophilia is a prominent feature in Churg-Strauss syndrome but has not been described in granulomatosis with polyangiitis (GPA) in a pediatric patient. We present a biopsy case that confirmed granulomatosis with polyangiitis with significant eosinophilia > 30% on the initial presentation. Etiologies that could account for eosinophilia were excluded during workup. The patient's presentation of pulmonary alveolar hemorrhage, conjunctivitis arthritis, high-titer cytoplasmic antineutrophil, PR3-ANCA antibodies, and cytoplasmic antibodies (cANCA) was consistent with a clinical picture of atypical GPA in a pediatric patient. This case presents a rare opportunity not only due to GPA's low incidence in the pediatric population but due to the unusual nature of significant eosinophilia in GPA. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2020, Saenz Rios et al.) |
| Databáze: | MEDLINE |
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