Longitudinal changes to quadriceps thickness demonstrate acute sarcopenia following admission to hospital for an exacerbation of chronic respiratory disease.

Autor: McAuley HJC; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Centre for Exercise and Rehabilitation Science, Institute for Lung Health, University Hospitals of Leicester NHS Trust, Leicester, UK., Harvey-Dunstan TC; Division of Physiotherapy and Rehabilitation Science, University of Nottingham, Nottingham, UK., Craner M; Centre for Exercise and Rehabilitation Science, Institute for Lung Health, University Hospitals of Leicester NHS Trust, Leicester, UK., Richardson M; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Singh SJ; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Centre for Exercise and Rehabilitation Science, Institute for Lung Health, University Hospitals of Leicester NHS Trust, Leicester, UK., Steiner MC; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Centre for Exercise and Rehabilitation Science, Institute for Lung Health, University Hospitals of Leicester NHS Trust, Leicester, UK., Greening NJ; Department of Respiratory Sciences, University of Leicester, Leicester, UK neil.greening@leicester.ac.uk.; Centre for Exercise and Rehabilitation Science, Institute for Lung Health, University Hospitals of Leicester NHS Trust, Leicester, UK.
Jazyk: angličtina
Zdroj: Thorax [Thorax] 2021 Jul; Vol. 76 (7), pp. 726-728. Date of Electronic Publication: 2020 Dec 22.
DOI: 10.1136/thoraxjnl-2020-215949
Abstrakt: Acute admission to hospital for an exacerbation of chronic respiratory disease (CRD) may impair skeletal muscle mass and function. We measured quadriceps thickness (Q thick ), as a surrogate marker of muscle mass, at hospital admission, discharge, 6 weeks and 3 months in 55 patients with CRD. Q thick fell by 8.3% during the period of hospitalisation, which was sustained at 6 weeks, and only partially recovered at 3 months. Sustained loss was most marked in patients readmitted during the follow-up period. Acute reduction in quadriceps muscle mass occurs during hospitalisation, with prolonged and variable recovery, which is prevented with subsequent hospital readmission.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE
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