Multidisciplinary lifestyle intervention to manage pancreatic cancer-related cachexia: a case report.

Autor:	Avancini A; Department of Medicine, Biomedical, Clinical & Experimental Sciences, University of Verona Hospital Trust, Verona 37134, Italy., Trestini I; Department of Medicine, Medical Oncology, University of Verona Hospital Trust, Verona 37134, Italy., Tregnago D; Department of Medicine, Medical Oncology, University of Verona Hospital Trust, Verona 37134, Italy., Cavallo A; Department of Neurosciences, Biomedicine & Movement Sciences, University of Verona, Verona 37134, Italy., Bragato M; Department of Neurosciences, Biomedicine & Movement Sciences, University of Verona, Verona 37134, Italy., Bonaiuto C; Department of Medicine, Medical Oncology, University of Verona Hospital Trust, Verona 37134, Italy., Lanza M; Department of Neurosciences, Biomedicine & Movement Sciences, University of Verona, Verona 37134, Italy., Milella M; Department of Medicine, Medical Oncology, University of Verona Hospital Trust, Verona 37134, Italy., Pilotto S; Department of Medicine, Medical Oncology, University of Verona Hospital Trust, Verona 37134, Italy.
Jazyk:	angličtina
Zdroj:	Future science OA [Future Sci OA] 2020 Nov 12; Vol. 7 (2), pp. FSO659. Date of Electronic Publication: 2020 Nov 12.
DOI:	10.2144/fsoa-2020-0165
Abstrakt:	Pancreatic cancer remains an aggressive disease, with a poor prognosis and a high risk of incurring into cachexia. Supportive care, such as exercise, nutritional and psychological support, may be effective in reducing functional loss, psychological distress and improving nutritional status. We report the effect of 12 weeks of multimodal lifestyle intervention in a 55-year-old female, diagnosed with unresectable body/tail pancreatic cancer and metastasis in the liver, bone, lymph node and lung, to counteract cachexia. The multimodal program resulted safe and feasible. Over 12 weeks, considerable improvements were found in body weight, health-related physical fitness, nutritional status, distress scores, anxiety and depression levels. These findings highlight the potential role of integrated supportive interventions to manage metastatic cancer and cancer-induced cachexia. Competing Interests: Financial & competing interests disclosure S Pilotto is supported by the Italian Association for Cancer Research (AIRC-IG 20583) and by the International Association for Lung Cancer (IASLC). M Milella reports personal fees from Pfizer, EUSA Pharma and Astra Zeneca, outside the submitted manuscript. S Pilotto received honoraria or speakers’ fee from Astra-Zeneca, Eli-Lilly, BMS, Boehringer Ingelheim, MSD and Roche, outside the submitted manuscript. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript. (© 2020 Alice Avancini, Ilaria Trestini, Daniela Tregnago et al.)
Databáze:	MEDLINE
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