Transthoracic mediastinal ultrasound in childhood tuberculosis: A review.

Autor: Ruby LC; Department of Paediatric Pulmonology, Immunology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany., Heuvelings CC; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Amsterdam University Medical Centers, Amsterdam Infection & Immunity, Amsterdam Public Health, University of Amsterdam, Amsterdam, The Netherlands., Grobusch MP; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Amsterdam University Medical Centers, Amsterdam Infection & Immunity, Amsterdam Public Health, University of Amsterdam, Amsterdam, The Netherlands., Andronikou S; Department of Radiology, The Children's Hospital of Philadelphia, USA; Department of Radiology, The Perelman School of Medicine, University of Pennsylvania, USA., Bélard S; Department of Paediatric Pulmonology, Immunology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany; Berlin Institute of Health, Berlin, Germany. Electronic address: sabine.belard@charite.de.
Jazyk: angličtina
Zdroj: Paediatric respiratory reviews [Paediatr Respir Rev] 2022 Mar; Vol. 41, pp. 40-48. Date of Electronic Publication: 2020 Dec 09.
DOI: 10.1016/j.prrv.2020.11.002
Abstrakt: Diagnosing childhood tuberculosis (TB) is challenging, and novel diagnostic tools are urgently needed. Mediastinal lymphadenopathy is a hallmark of primary pulmonary TB (PTB) in children. We aimed to summarise available methodological and diagnostic data of transthoracic mediastinal ultrasound for childhood TB. Literature review identified two prospective and three retrospective studies, a case report, and a technical report including cases. All reported on suprasternal scanning of the mediastinum; additional parasternal scanning was reported by five studies. The proportion of children with lymphadenopathy detected by mediastinal ultrasound ranged between 15% and 85%, with studies including both supra- and parasternal scanning achieving higher detection ratios. Three retrospective studies reported mediastinal lymphadenopathy on ultrasound for most cases presenting with a normal or inconclusive CXR. Data on ultrasound for mediastinal lymphadenopathy in children are limited but indicate that mediastinal ultrasound can successfully detect mediastinal lymphadenopathy in children with TB.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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