Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote.

Autor: Spencer PS; Oregon Health & Science University, Portland, Oregon, USA., Palmer VS; Oregon Health & Science University, Portland, Oregon, USA., Kihira T; Kansai University of Health Sciences, Japan., Yoshida S; Kansai University of Health Sciences, Japan., Reis J; University of Strasbourg, Strasbourg, France., Yabushita M; Nagoya University, Nagoya, Japan., Yase Y; Wakayama Medical University, Wakayama, Japan.
Jazyk: angličtina
Zdroj: ENeurologicalSci [eNeurologicalSci] 2020 Dec 25; Vol. 22, pp. 100308. Date of Electronic Publication: 2020 Dec 25 (Print Publication: 2021).
DOI: 10.1016/j.ensci.2020.100308
Abstrakt: Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism-dementia Complex (ALS/PDC) is a disappearing neurodegenerative disease in three former high-incidence foci of the U.S. territory of Guam, Papua-Indonesia (New Guinea) and Kii Peninsula, Honshu Island, Japan (Muro disease). We report additional data that associate medicinal use of cycad seed to Muro disease in the southern Kozagawa focus of ALS/PDC. In the other two ALS/PDC-affected populations, cycad seed was used as a traditional topical medicine in New Guinea and Guam and, additionally, for food on Guam.
(© 2020 The Authors.)
Databáze: MEDLINE