Sustainable polypyrrole-based magnetic-microextraction of phthalates from jellies and apple-based beverages prior to tandem mass spectrometry analysis.

Autor: Rodríguez-Ramos R; Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Universidad de La Laguna (ULL). Avda. Astrofísico Fco. Sánchez, s/n°. 38206 San Cristóbal de La Laguna, España., Socas-Rodríguez B; Laboratory of Foodomics, Institute of Food Science Research, CIAL, CSIC, Nicolás Cabrera 9, Madrid, 28049, Spain. Electronic address: barbara.socas@csic.es., Santana-Mayor Á; Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Universidad de La Laguna (ULL). Avda. Astrofísico Fco. Sánchez, s/n°. 38206 San Cristóbal de La Laguna, España., Salazar-Carballo PÁ; Laboratorio de Sensores, Biosensores y Materiales Avanzados, Departamento de Medicina Física y Farmacología, Sección de Medicina, Facultad de Ciencias de la Salud, Universidad de La Laguna (ULL), Campus de Ofra, s/n°. 38071 San Cristóbal de La Laguna, España., Rodríguez-Delgado MÁ; Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Universidad de La Laguna (ULL). Avda. Astrofísico Fco. Sánchez, s/n°. 38206 San Cristóbal de La Laguna, España. Electronic address: mrguez@ull.edu.es.
Jazyk: angličtina
Zdroj: Journal of chromatography. A [J Chromatogr A] 2021 Jan 25; Vol. 1637, pp. 461858. Date of Electronic Publication: 2020 Dec 29.
DOI: 10.1016/j.chroma.2020.461858
Abstrakt: Synthesised polypyrrole-coated Fe 3 O 4 magnetic nanoparticles have been successfully characterised and applied as sorbent for the magnetic-micro-dispersive solid-phase extraction of eleven phthalic acid esters from jelly and apple-based beverage matrices widely consumed by the population and, especially, by children. Sorbent was synthesised through chemical coprecipitation and subsequently characterised by different techniques. The influence of several parameters on the extraction efficiency was exhaustively evaluated using a step-by-step strategy. The separation and quantification of the selected phthalates were performed by ultra-high performance liquid chromatography coupled to tandem mass spectrometry. The validation of the methodology was carried out for jellies and apple-based beverages, employing dihexyl phthalate-3,4,5,6-d 4 as the surrogate standard. Relative recovery values were in the range 70-114% for both matrices and relative standard deviations below 20% were obtained. The limits of quantification of the method were found in the range 0.147-0.416 µg/L. Feasibility of the developed methodology was proved by the analysis of commercialised jelly and apple-based beverage products.
Competing Interests: Declaration of Competing Interest Authors declare no conflict of interest.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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