Measuring particle size distribution and mass concentration of nanoplastics and microplastics: addressing some analytical challenges in the sub-micron size range.

Autor: Caputo F; Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim, Norway. Electronic address: fanny.caputo@sintef.no., Vogel R; School of Mathematics and Physics, The University of Queensland, St Lucia, QLD 4072, Australia; IZON Science Ltd., Burnside, Christchurch 8053, New Zealand., Savage J; LBCAM, Department of Clinical Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland., Vella G; LBCAM, Department of Clinical Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland., Law A; NanoFCM Co., Ltd, Medicity, Building D6, Thane Road, Nottingham NG90 6BH, UK., Della Camera G; Institute of Biochemistry and Cell Biology, CNR, Via P. Castellino 111, 80131 Napoli, Italy., Hannon G; LBCAM, Department of Clinical Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland., Peacock B; NanoFCM Co., Ltd, Medicity, Building D6, Thane Road, Nottingham NG90 6BH, UK., Mehn D; European Commission, Joint Research Centre (JRC), Ispra, Italy., Ponti J; European Commission, Joint Research Centre (JRC), Ispra, Italy., Geiss O; European Commission, Joint Research Centre (JRC), Ispra, Italy., Aubert D; NanoFCM Co., Ltd, Medicity, Building D6, Thane Road, Nottingham NG90 6BH, UK., Prina-Mello A; LBCAM, Department of Clinical Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland; AMBER Centre, CRANN Institute, Trinity College Dublin, Dublin, Ireland., Calzolai L; European Commission, Joint Research Centre (JRC), Ispra, Italy.
Jazyk: angličtina
Zdroj: Journal of colloid and interface science [J Colloid Interface Sci] 2021 Apr 15; Vol. 588, pp. 401-417. Date of Electronic Publication: 2021 Jan 07.
DOI: 10.1016/j.jcis.2020.12.039
Abstrakt: Hypothesis: The implementation of the proposal from the European Chemical Agency (ECHA) to restrict the use of nanoplastics (NP) and microplastics (MP) in consumer products will require reliable methods to perform size and mass-based concentration measurements. Analytical challenges arise at the nanometre to micrometre interface, e.g., 800 nm-10 µm, where techniques applicable at the nanometre scale reach their upper limit of applicability and approaches applicable at the micrometre scale must be pushed to their lower limits of detection.
Experiments: Herein, we compared the performances of nine analytical techniques by measuring the particle size distribution and mass-based concentration of polystyrene mixtures containing both nano and microparticles, with the educational aim to underline applicability and limitations of each technique.
Findings: Light scattering-based measurements do not have the resolution to distinguish multiple populations in polydisperse samples. Nanoparticle tracking analysis (NTA), nano-flowcytometry (nFCM) and asymmetric flow field flow fractionation hyphenated with multiangle light scattering (AF4-MALS) cannot measure particles in the micrometre range. Static light scattering (SLS) is not able to accurately detect particles below 200 nm, and similarly to transmission electron microscopy (TEM) and flow cytometry (FCM), is not suitable for accurate mass-based concentration measurements. Alternatives for high-resolution sizing and concentration measurements in the size range between 60 nm and 5 µm are tunable resistive pulse sensing (TRPS) and centrifugal liquid sedimentation (CLS), that can bridge the gap between the nanometre and micrometre range.
Competing Interests: Declaration of Competing Interest RV is a contractor at IZON Science and JM is employed by IZON Science and their contributions to this paper were made as part of their contract/employment. AL, BP, DA are employees of nano Flow Cytometry and their contributions to this paper were made as part of their employment.
(Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: