Chemotherapy Knowledge Base Management in the Era of Precision Oncology.

Autor: Rubinstein SM; University of North Carolina at Chapel Hill, Chapel Hill, NC., Sethi T; Yale University, New Haven, CT., Venepalli NK; University of Illinois at Chicago College of Medicine, Chicago, IL., Gyawali B; Queens University, Kingston, Ontario, Canada., Schwartz C; University of Illinois at Chicago College of Medicine, Chicago, IL., Rivera DR; Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD., Yang PC; Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA., Warner JL; Vanderbilt University Medical Center, Nashville, TN.
Jazyk: angličtina
Zdroj: JCO clinical cancer informatics [JCO Clin Cancer Inform] 2021 Jan; Vol. 5, pp. 30-35.
DOI: 10.1200/CCI.20.00076
Abstrakt: Cancer medicine has grown increasingly complex in recent years with the advent of precision oncology and wide utilization of multidrug regimens. Representing this increasingly granular knowledge is a significant challenge. As users and managers of a freely available chemotherapy drug and regimen database, we describe the changes we have made to accommodate these challenges. These include the development of a domain ontology and increased granularity in the classification of cancer types on the website.
Databáze: MEDLINE