[Pharmaceutical interventions and clinical outcomes in an antimicrobial stewardship program].
| Autor: | Holguín H; Clínica Medellín S.A - Quironsalud, Grupo de investigación Promoción y Prevención Farmacéutica, Universidad de Antioquia, Colombia., Amariles P; Grupo de Investigación Promoción y Prevención Farmacéutica, Universidad de Antioquia, Colombia., Ospina W; Clínica Medellín S.A., Colombia., Pinzón M; Clínica Medellín S.A., Colombia., Granados J; Grupo de Investigación Promoción y Prevención Farmacéutica, Universidad de Antioquia, Colombia. |
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| Jazyk: | Spanish; Castilian |
| Zdroj: | Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia [Rev Chilena Infectol] 2020 Aug; Vol. 37 (4), pp. 343-348. |
| DOI: | 10.4067/S0716-10182020000400343 |
| Abstrakt: | Background: The pharmacist's participation in the antimicrobial stewardship program (AMSP) has been associated with better outcomes. Aims: To describe the pharmaceutical interventions and clinical outcomes of a PGA focused on broad-spectrum antibiotics in hospitalized patients in a tertiary healthcare setting. Method: Prospective observational study in patients admitted to a tertiary healthcare setting between August-2016 and September-2017. In the context of a AMSP, a pharmacist training in infectious diseases evaluated and intervened antibiotic therapy, with the infectious disease specialist, who performed relevant modification of the antibiotic therapy. In addition, the clinical outcome was evaluated and documented. Results: 258 patients were included. 16.1% of antibiotics were assessed as not indicated. A total of 126 pharmaceutical interventions were performed with 82.5% acceptance. The main outcome was the clinical and/or microbiological cure of infection. Conclusion: The problem associated with the antibiotic most frequently in the study population was the antimicrobial spectrum. Being consistent, de-escalation was the pharmaceutical intervention with the highest prevalence. A high percentage of acceptance of the interventions performed by the pharmacist in the environment of the PGAn was considered. Clinical and/or microbiological cure was the main cause of hospital discharge. |
| Databáze: | MEDLINE |
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