The Effect of Partnership Presence and Support on HIV Viral Suppression Among Serodiscordant Partnered and Single Heterosexual HIV-Positive Individuals in Brazil.

Autor: Baker Z; Division of Urology, Children's Hospital Los Angeles, 4650 W. Sunset Blvd, MS #114, Los Angeles, CA, 90027, USA. zobaker@chla.usc.edu., Gorbach P; Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles (UCLA), Los Angeles, CA, USA., de Melo MG; Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil., Varela I; Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil., Sprinz E; Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil., Santos B; Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil., de Melo Rocha T; Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil., Simon M; Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil., Almeida M; Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil., Lira R; Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil., Chaves MC; Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil., Kerin T; Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, CA, USA., Nielsen-Saines K; Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Jazyk: angličtina
Zdroj: AIDS and behavior [AIDS Behav] 2021 Jun; Vol. 25 (6), pp. 1946-1953. Date of Electronic Publication: 2021 Jan 02.
DOI: 10.1007/s10461-020-03124-5
Abstrakt: HIV-negative individuals in serodiscordant partnerships experience reduced risk of HIV acquisition when their partners adhere to ART and achieve undetectable viral loads. Partnership support may encourage ART adherence, reducing viral load and the risk of HIV transmission. This study aims to determine whether HIV viral suppression is associated with partnership status and partnership support among 201 HIV positive (HIV+ individuals in serodiscordant partnerships and 100 HIV+ unpartnered individuals receiving care at Hospital Nossa Senhora da Conceição in Porto Alegre, Brazil between 2014 and 2016. Clinical data and patient-reported questionnaire data were assessed, and propensity scores were used to control for confounding variables in adjusted logistic regression models. Viral suppression did not significantly differ between HIV+ partnered (78.5% virally suppressed) and unpartnered (76.0% virally suppressed) individuals. Among individuals in partnerships, viral suppression was significantly associated with having a partner who attended monthly clinic visits (AOR 2.99; 95% CI 1.00-8.93). Instrumental social support-attending monthly visits-may improve the odds of viral suppression among HIV+ individuals in serodiscordant relationships.
Databáze: MEDLINE