Non-invasive Ultrasonographic Score for Assessment of the Severity of Inflammatory Bowel Disease.

Autor:	Marin AM; Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania., Calapod OP; Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania; Gastroenterology Department, Bucharest Emergency University Hospital, Bucharest, Romania., Moldoveanu AC; Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania; Gastroenterology Department, Bucharest Emergency University Hospital, Bucharest, Romania., Tribus LC; Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania; Gastroenterology Department, Bucharest Emergency University Hospital, Bucharest, Romania. Electronic address: ltribusro@yahoo.com., Fierbințeanu-Braticevici C; Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania; Gastroenterology Department, Bucharest Emergency University Hospital, Bucharest, Romania.
Jazyk:	angličtina
Zdroj:	Ultrasound in medicine & biology [Ultrasound Med Biol] 2021 Apr; Vol. 47 (4), pp. 932-940. Date of Electronic Publication: 2020 Dec 30.
DOI:	10.1016/j.ultrasmedbio.2020.11.026
Abstrakt:	Intestinal ultrasound and shear wave elastography have gained increasing interest because of their promising results in the assessment of inflammatory bowel disease. The aim of this study was to find an ultrasonographic score to replace invasive endoscopic procedures for the management of these patients. The score includes ultrasound parameters that correlate well with clinical severity scales and inflammatory markers: bowel wall thickness, the Limberg score, disease extension and acoustic radiation force impulse measurements. The score proved to be well correlated with the Harvey Bradshaw Index, the Mayo score, C-reactive protein and fecal calprotectin. For Crohn's disease, a cutoff value of 8 points could identify active disease with 81.81% sensitivity and 83% specificity, while for ulcerative colitis, a cutoff value of 7 points could discriminate between remission and relapse with 86.85% sensitivity and 94% specificity. In conclusion, our ultrasonographic score can differentiate relapse from remission in inflammatory bowel disease. Competing Interests: Conflict of interest disclosure The authors declare that there are no conflicts of interest. (Copyright © 2020 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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