Healthful dietary patterns and risk of end-stage kidney disease: the Singapore Chinese Health Study.

Autor:	Geng TT; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Jafar TH; Health Services and Systems Research, Duke-NUS Medical School, Singapore.; Department of Renal Medicine, Singapore General Hospital, Singapore., Neelakantan N; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Yuan JM; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore.; Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA., Koh WP; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore.
Jazyk:	angličtina
Zdroj:	The American journal of clinical nutrition [Am J Clin Nutr] 2021 Mar 11; Vol. 113 (3), pp. 675-683.
DOI:	10.1093/ajcn/nqaa348
Abstrakt:	Background: Although adherence to healthful dietary patterns has been associated with a lower risk of kidney function decline in Western populations, evidence in Asian populations remains scanty. Objectives: We examined predefined dietary patterns, namely, the Alternate Healthy Eating Index-2010 (AHEI-2010), the Dietary Approaches to Stop Hypertension (DASH), and the alternate Mediterranean diet (aMED), in relation to risk of end-stage kidney disease (ESKD). Methods: We included 56,985 Chinese adults (aged 45-74 y) in the Singapore Chinese Health Study who were free of cancer, stroke, coronary artery disease, and ESKD at recruitment (1993-1998). Dietary pattern scores were calculated based on a validated 165-item FFQ. AHEI-2010 and aMED scores were modified by excluding the alcohol intake component because daily drinking has been associated with a higher risk of ESKD in our study population. We identified 1026 ESKD cases over a median follow-up of 17.5 y via linkage with the nationwide Singapore Renal Registry. Multivariable Cox regression models were used to compute HRs and their 95% CIs. Results: Higher scores of all 3 dietary patterns were associated with lower ESKD risk in a dose-dependent manner. Compared with the lowest quintiles, the multivariable-adjusted HRs (95% CIs) of ESKD were 0.75 (0.61, 0.92) for the highest quintile of AHEI-2010, 0.67 (0.54, 0.84) for DASH, and 0.73 (0.59, 0.91) for aMED (all P-trend ≤ 0.004). These inverse associations were stronger with increasing BMI (in kg/m2), and the HRs for the diet-ESKD association were lowest in the obese (BMI ≥ 27.5), followed by the overweight (BMI = 25 to <27.5) participants, compared with those in lower BMI categories; the P-interaction values between BMI and diet scores were 0.03 for AHEI-2010, 0.004 for aMED, and 0.06 for DASH. Conclusions: Adherence to healthful dietary patterns was associated with a lower ESKD risk in an Asian population, especially in overweight or obese individuals. (© The Author(s) 2020. Published by Oxford University Press on behalf of the American Society for Nutrition.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu