Probing axial metal distribution on biopolymer-based layer-by-layer films for antimicrobial use.

Autor: Taketa TB; School of Chemical Engineering, Unicamp, 500 Albert Einstein Av. 13083-852, Campinas, SP, Brazil. Electronic address: t115189@dac.unicamp.br., Bataglioli RA; School of Chemical Engineering, Unicamp, 500 Albert Einstein Av. 13083-852, Campinas, SP, Brazil. Electronic address: rogerbataglioli@gmail.com., Rocha Neto JBM; School of Chemical Engineering, Unicamp, 500 Albert Einstein Av. 13083-852, Campinas, SP, Brazil. Electronic address: jbmrneto@gmail.com., Beppu MM; School of Chemical Engineering, Unicamp, 500 Albert Einstein Av. 13083-852, Campinas, SP, Brazil. Electronic address: beppu@unicamp.br.
Jazyk: angličtina
Zdroj: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2021 Mar; Vol. 199, pp. 111505. Date of Electronic Publication: 2020 Dec 05.
DOI: 10.1016/j.colsurfb.2020.111505
Abstrakt: This study presents the axial molar composition of polysaccharide-based polyelectrolyte multilayer (PEM) films loaded with silver ions for antimicrobial applications. Individual polymers (chitosan, hyaluronan or alginate) and silver composition were determined using X-Ray Photoelectron Spectroscopy coupled with C 60 + cluster ion sputtering technique, while the influence of silver loading on film topography was assessed using Atomic Force Microscopy. Despite the use of the layer-by-layer approach for film assembly, these PEM films present a non-stratified, nanoblend-like, polymer composition, with a nearly uniform metal distribution over the axial direction. Results also show surface antimicrobial activity towards Staphylococcus aureus bacteria and Candida albicans fungi over 20 h for hyaluronan/chitosan PEM, which is associated with its higher silver loading capacity. The interplay of bulk film composition and surface properties may provide valuable insights for engineering advanced materials with controlled spatio-temporal behavior.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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