Epitheliotropic T-cell lymphoma in 2 half-sibling bontebok.

Autor: Imanse SM; Michigan State University Veterinary Diagnostic Laboratory, Lansing, MI.; Current addresses: Zoological Pathology Program, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Brookfield, IL., Monahan CF; Michigan State University Veterinary Diagnostic Laboratory, Lansing, MI.; New Hampshire Veterinary Diagnostic Laboratory, University of New Hampshire, Durham, NH., Thompson KA; Binder Park Zoo, Battle Creek, MI., Marrow JC; Binder Park Zoo, Battle Creek, MI.; Houston Zoo, Houston, TX., Corner SM; Michigan State University Veterinary Diagnostic Laboratory, Lansing, MI.
Jazyk: angličtina
Zdroj: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest] 2021 Mar; Vol. 33 (2), pp. 370-374. Date of Electronic Publication: 2020 Dec 29.
DOI: 10.1177/1040638720984115
Abstrakt: We diagnosed epitheliotropic T-cell lymphoma of the forestomachs in 2 aged, half-sibling, zoo-managed bontebok ( Damaliscus pygargus pygargus ). One bontebok also had mesenteric lymph node and cutaneous involvement. Both animals had a history of chronic abdominal distension and diminished body condition that resulted in euthanasia. At autopsy, both animals had marked ruminal distension with diffusely blunted ruminal papillae and reticular crests. In case 1, there was an increased amount and particle length of the ruminoreticular fibrous material with scant fluid, and a 2-cm diameter focus of cutaneous crusting adjacent to a mammary teat. In case 2, the rumen and reticulum were fluid-distended with decreased fibrous material. Histologically in case 1, the rumen, reticulum, omasum, and skin had intraepithelial nests and sheets of neoplastic small lymphocytes; in case 2, the rumen and reticulum had a similar neoplastic cell population. Immunohistochemically, neoplastic lymphocytes were immunoreactive for CD3 and negative for CD20, confirming the diagnosis of epitheliotropic T-cell lymphoma.
Databáze: MEDLINE