Virxicon: a lexicon of viral sequences.
| Autor: | Kudla M; Institute of Computing Science and European Centre for Bioinformatics and Genomics, Poznan University of Technology, Poznan 60-965, Poland.; Saxon Institute for Computational Intelligence and Machine Learning, University of Applied Sciences Mittweida, Mittweida 09648, Germany., Gutowska K; Institute of Computing Science and European Centre for Bioinformatics and Genomics, Poznan University of Technology, Poznan 60-965, Poland.; Department of Structural Bioinformatics, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan 61-704, Poland., Synak J; Institute of Computing Science and European Centre for Bioinformatics and Genomics, Poznan University of Technology, Poznan 60-965, Poland., Weber M; Saxon Institute for Computational Intelligence and Machine Learning, University of Applied Sciences Mittweida, Mittweida 09648, Germany., Bohnsack KS; Saxon Institute for Computational Intelligence and Machine Learning, University of Applied Sciences Mittweida, Mittweida 09648, Germany., Lukasiak P; Institute of Computing Science and European Centre for Bioinformatics and Genomics, Poznan University of Technology, Poznan 60-965, Poland.; Department of Structural Bioinformatics, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan 61-704, Poland., Villmann T; Saxon Institute for Computational Intelligence and Machine Learning, University of Applied Sciences Mittweida, Mittweida 09648, Germany., Blazewicz J; Institute of Computing Science and European Centre for Bioinformatics and Genomics, Poznan University of Technology, Poznan 60-965, Poland.; Department of Structural Bioinformatics, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan 61-704, Poland., Szachniuk M; Institute of Computing Science and European Centre for Bioinformatics and Genomics, Poznan University of Technology, Poznan 60-965, Poland.; Department of Structural Bioinformatics, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan 61-704, Poland. |
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| Jazyk: | angličtina |
| Zdroj: | Bioinformatics (Oxford, England) [Bioinformatics] 2021 Apr 01; Vol. 36 (22-23), pp. 5507-5513. |
| DOI: | 10.1093/bioinformatics/btaa1066 |
| Abstrakt: | Motivation: Viruses are the most abundant biological entities and constitute a large reservoir of genetic diversity. In recent years, knowledge about them has increased significantly as a result of dynamic development in life sciences and rapid technological progress. This knowledge is scattered across various data repositories, making a comprehensive analysis of viral data difficult. Results: In response to the need for gathering a comprehensive knowledge of viruses and viral sequences, we developed Virxicon, a lexicon of all experimentally acquired sequences for RNA and DNA viruses. The ability to quickly obtain data for entire viral groups, searching sequences by levels of taxonomic hierarchy-according to the Baltimore classification and ICTV taxonomy-and tracking the distribution of viral data and its growth over time are unique features of our database compared to the other tools. Availabilityand Implementation: Virxicon is a publicly available resource, updated weekly. It has an intuitive web interface and can be freely accessed at http://virxicon.cs.put.poznan.pl/. (© The Author(s) 2020. Published by Oxford University Press.) |
| Databáze: | MEDLINE |
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