Microfluidic devices for the detection of viruses: aspects of emergency fabrication during the COVID-19 pandemic and other outbreaks.
| Autor: | Berkenbrock JA; Department of Electrical and Computer Engineering, University of Saskatchewan, Saskatoon, SK, Canada., Grecco-Machado R; Department of Anatomy, Physiology and Pharmacology, University of Saskatchewan, Saskatoon, SK, Canada., Achenbach S; Department of Electrical and Computer Engineering, University of Saskatchewan, Saskatoon, SK, Canada. |
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| Jazyk: | angličtina |
| Zdroj: | Proceedings. Mathematical, physical, and engineering sciences [Proc Math Phys Eng Sci] 2020 Nov; Vol. 476 (2243), pp. 20200398. Date of Electronic Publication: 2020 Nov 04. |
| DOI: | 10.1098/rspa.2020.0398 |
| Abstrakt: | Extensive testing of populations against COVID-19 has been suggested as a game-changer quest to control the spread of this contagious disease and to avoid further disruption in our social, healthcare and economical systems. Nonetheless, testing millions of people for a new virus brings about quite a few challenges. The development of effective tests for the new coronavirus has become a worldwide task that relies on recent discoveries and lessons learned from past outbreaks. In this work, we review the most recent publications on microfluidics devices for the detection of viruses. The topics of discussion include different detection approaches, methods of signalling and fabrication techniques. Besides the miniaturization of traditional benchtop detection assays, approaches such as electrochemical analyses, field-effect transistors and resistive pulse sensors are considered. For emergency fabrication of quick test kits, the local capabilities must be evaluated, and the joint work of universities, industries, and governments seems to be an unequivocal necessity. Competing Interests: We declare we have no competing interests. (© 2020 The Authors.) |
| Databáze: | MEDLINE |
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