Anaplastic Carcinoma of the Pancreas: Clinical and Morphological Characteristics.

Autor: Podzolkov VI; Department of Faculty Therapy No. 2, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russian Federation., Pokrovskaya AE; Department of Faculty Therapy No. 2, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russian Federation., Vargina TS; Department of Faculty Therapy No. 2, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russian Federation., Ponomarev AB; Department of Pathological Anatomy, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russian Federation., Kogan YA; Department of Pathological Anatomy, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russian Federation., Lerner JV; Department of Pathological Anatomy, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russian Federation.
Jazyk: angličtina
Zdroj: Case reports in gastroenterology [Case Rep Gastroenterol] 2020 Nov 24; Vol. 14 (3), pp. 624-631. Date of Electronic Publication: 2020 Nov 24 (Print Publication: 2020).
DOI: 10.1159/000511037
Abstrakt: Anaplastic pancreatic carcinoma is a very rare histological subtype of pancreatic cancer, which is characterized by a more aggressive course than for conventional ductal adenocarcinoma. In this article, we consider the features of the clinical course, the difficulties of diagnosis in connection with the absence of pathognomonic signs of pancreatic cancer, and the morphological picture of this disease in a patient 60 years of age. This clinical case clearly demonstrates the complexities of the pancreatic carcinoma diagnosis, fast disease progression, and extremely unfavorable prognosis. It is important for clinicians to remember that this pathology often has a subclinical course, and the oncomarker levels are not always true.
Competing Interests: The authors have no conflicts of interest to declare.
(Copyright © 2020 by S. Karger AG, Basel.)
Databáze: MEDLINE
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