Prevalence of hepatitis B virus infection in pregnant women with and without HIV in Jos, Nigeria.

Autor:	Magaji FA; Jos University Teaching Hospital, Jos, Nigeria; Department of Obstetrics and Gynaecology, Jos, Nigeria. Electronic address: magajif@unijos.edu.ng., Okolo MO; Jos University Teaching Hospital, Jos, Nigeria; Department of Medical Microbiology, Jos, Nigeria., Yiltok ES; Jos University Teaching Hospital, Jos, Nigeria; Department of Paediatrics, Jos, Nigeria., Golit W; Jos University Teaching Hospital, Jos, Nigeria; Department of Obstetrics and Gynaecology, Plateau State Specialist Hospital, Jos, Nigeria., Anzaku SA; Department of Obstetrics and Gynaecology, Bingham University Teaching Hospital, Jos, Nigeria., Ogwuche J; Maternal and Child Health Unit, Our Lady of Apostles Hospital, Jos, Nigeria., Pam VC; Jos University Teaching Hospital, Jos, Nigeria; Department of Obstetrics and Gynaecology, Jos, Nigeria., Ocheke AN; Jos University Teaching Hospital, Jos, Nigeria; Department of Obstetrics and Gynaecology, Jos, Nigeria., Musa J; Jos University Teaching Hospital, Jos, Nigeria; Department of Obstetrics and Gynaecology, Jos, Nigeria., Isichie C; Jos University Teaching Hospital, Jos, Nigeria; Faith Alive Foundation Hospital, Jos, Nigeria., Imade GE; Department of Obstetrics and Gynaecology, Jos, Nigeria., Mutihir JT; Jos University Teaching Hospital, Jos, Nigeria; Department of Obstetrics and Gynaecology, Jos, Nigeria., Ugwu BT; Jos University Teaching Hospital, Jos, Nigeria; Department of Surgery, Jos, Nigeria., Agbaji O; Jos University Teaching Hospital, Jos, Nigeria; Department of Internal Medicine, Jos, Nigeria., Sagay SA; Jos University Teaching Hospital, Jos, Nigeria; Department of Obstetrics and Gynaecology, Jos, Nigeria., Zoakah AI; Jos University Teaching Hospital, Jos, Nigeria; Department of Community Medicine, Jos, Nigeria., Cohn SE; Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2021 Mar; Vol. 104, pp. 276-281. Date of Electronic Publication: 2021 Jan 28.
DOI:	10.1016/j.ijid.2020.12.058
Abstrakt:	Objective: To compare the prevalence of hepatitis B virus (HBV) in pregnant women with and without human immunodeficiency virus (HIV) in Jos, Nigeria. Methods: This comparative cross-sectional study of pregnant women was undertaken between 1 November 2017 and 30 April 2018. Informed consent was obtained, demographic data and predictors for HBV were collected, and all women were screened for HIV and HBV. Descriptive statistics and multivariate analyses using STATA Version 15 were performed. Results: Of 3238 women enrolled, 12.6% and 7.2% of those with and without HIV had HBV, respectively (P = 0.01). Women with HIV, higher parity [adjusted odds ratio (aOR) 0.68, P < 0.01], lower gestational age (aOR 1.04, P < 0.01) and without prior HBV vaccination (aOR 0.40, P < 0.01) were significantly more likely to have HBV infection. Conclusions: Among pregnant women, the prevalence of HBV was higher among those with HIV. Predictors of HBV included being multigravida or grand-multigravida, registration for antenatal care before 20 weeks of gestation, and no prior HBV vaccination. In settings with endemic HBV and HIV, integration of effective HBV and HIV prevention services could greatly decrease the transmission and prevalence of HBV. (Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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