The effects of zinc amino acid complex on biomarkers of gut integrity, inflammation, and metabolism in heat-stressed ruminants.
| Autor: | Opgenorth J; Department of Animal Science, Iowa State University, Ames 50011., Abuajamieh M; Department of Animal Science, Iowa State University, Ames 50011., Horst EA; Department of Animal Science, Iowa State University, Ames 50011., Kvidera SK; Department of Animal Science, Iowa State University, Ames 50011., Johnson JS; Department of Animal Science, Iowa State University, Ames 50011., Mayorga EJ; Department of Animal Science, Iowa State University, Ames 50011., Sanz-Fernandez MV; Department of Animal Science, Iowa State University, Ames 50011., Al-Qaisi MA; Department of Animal Science, Iowa State University, Ames 50011., DeFrain JM; Zinpro Corporation, Eden Prairie, MN 55344., Kleinschmit DH; Zinpro Corporation, Eden Prairie, MN 55344., Gorden PJ; Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames 50011., Baumgard LH; Department of Animal Science, Iowa State University, Ames 50011. Electronic address: baumgard@iastate.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of dairy science [J Dairy Sci] 2021 Feb; Vol. 104 (2), pp. 2410-2421. Date of Electronic Publication: 2020 Dec 23. |
| DOI: | 10.3168/jds.2020-18909 |
| Abstrakt: | Study objectives were to evaluate the effects of replacing 40 mg/kg of dietary Zn from Zn sulfate (ZS) with Zn amino acid complex (ZA; Zinpro Corporation, Eden Prairie, MN) on inflammation and intestinal integrity in heat-stressed and pair-fed (PF) ruminants. Forty Holstein steers (173.6 ± 4.9 kg) were randomly assigned to 1 of 5 dietary-environmental treatments: (1) thermoneutral (TN) ad libitum with 75 mg/kg of dry matter (DM) ZS (ZSCON); (2) TN pair-fed with 75 mg/kg DM ZS (ZSPF); (3) TN pair-fed with 40 mg/kg DM ZA and 35 mg/kg DM ZS (ZAPF); (4) heat stress (HS) ad libitum with 75 mg/kg DM ZS (ZSHS); and (5) HS ad libitum 40 mg/kg DM ZA and 35 mg/kg DM ZS (ZAHS). Before study initiation, calves were fed their respective diets for 21 d. Following the pre-feeding phase, steers were transferred into environmental chambers and were subjected to 2 successive experimental periods. During period 1 (5 d), all steers were fed their respective diets ad libitum and housed in TN conditions (20.2 ± 1.4°C, 30.4 ± 4.3% relative humidity). During period 2 (6 d), ZSHS and ZAHS steers were exposed to cyclical HS conditions (27.1 ± 1.5°C to 35.0 ± 2.9°C, 19.3 ± 3.5% relative humidity), whereas the ZSCON, ZSPF, and ZAPF steers remained in TN conditions and were fed ad libitum or pair-fed relative to their ZSHS and ZAHS counterparts. Overall, steers exposed to HS had markedly increased rectal temperature (0.83°C), respiration rate (26 breaths per min), and skin temperature (8.00°C) relative to TN treatments. Rectal temperature from ZAHS steers was decreased (0.24°C) on d 4 to 6 of HS relative to ZSHS steers. Regardless of diet, HS decreased DMI (18%) relative to ZSCON steers. Circulating glucose from HS and PF steers decreased (16%) relative to ZSCON steers. Heat stress and nutrient restriction increased circulating nonesterified fatty acids 2- and 3-fold, respectively, compared with ZSCON steers. Serum amyloid A increased ~2-fold in PF relative to ZSCON and HS steers. We detected no treatment effect on blood pH; however, ZAHS steers had increased HCO (The Authors. Published by Elsevier Inc. and Fass Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).) |
| Databáze: | MEDLINE |
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