Molecular analysis of a rare case of low-grade primary peritoneal serous carcinoma in a male.
| Autor: | Makarenko VV; Department of Pathology, University of Massachusetts Memorial Medical Center, Worcester, MA, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Kandil D; Department of Pathology, University of Massachusetts Memorial Medical Center, Worcester, MA, USA., Cosar EF; Department of Pathology, University of Massachusetts Memorial Medical Center, Worcester, MA, USA., Hutchinson L; Department of Pathology, University of Massachusetts Memorial Medical Center, Worcester, MA, USA., Khan A; Department of Pathology, University of Massachusetts Memorial Medical Center, Worcester, MA, USA.; Department of Pathology, University of Massachusetts Medical School-Baystate, Springfield, MA, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Rare tumors [Rare Tumors] 2020 Dec 09; Vol. 12, pp. 2036361320979219. Date of Electronic Publication: 2020 Dec 09 (Print Publication: 2020). |
| DOI: | 10.1177/2036361320979219 |
| Abstrakt: | Primary peritoneal serous carcinomas (PPSC) are exceedingly rare in male patients. Only a few cases were reported, and mostly with the limited immunophenotypical characterization. No molecular analysis of PPSC in males has been previously performed. We here describe another case of PPSC in a male patient. A comprehensive molecular analysis of the tumor revealed SF3B1 gene mutation as a possible driver. Competing Interests: Conflict of interest: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. (© The Author(s) 2020.) |
| Databáze: | MEDLINE |
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