A rare presentation of Sinonasal Undifferentiated Carcinoma with brain metastasis and para-aortic mass.

Autor:	Sarangi S; All India Institute of Medical Sciences, Department of Pathology & Laboratory Medicine, Jodhpur, Rajasthan., Khera S; All India Institute of Medical Sciences, Department of Pathology & Laboratory Medicine, Jodhpur, Rajasthan., Vishwajeet V; All India Institute of Medical Sciences, Department of Pathology & Laboratory Medicine, Jodhpur, Rajasthan., Meshram V; All India Institute of Medical Sciences, Department of Forensic Medicine and Toxicology, Jodhpur, Rajasthan., Setia P; All India Institute of Medical Sciences, Department of Forensic Medicine and Toxicology, Jodhpur, Rajasthan., Malik A; All India Institute of Medical Sciences, Department of Pathology & Laboratory Medicine, Jodhpur, Rajasthan.
Jazyk:	angličtina
Zdroj:	Autopsy & case reports [Autops Case Rep] 2020 Nov 20; Vol. 10 (4), pp. e2020222. Date of Electronic Publication: 2020 Nov 20.
DOI:	10.4322/acr.2020.222
Abstrakt:	Sinonasal Undifferentiated carcinoma (SNUC) comprises 3% of the head and neck tumors, including metastatic neoplasms. Herein we report the case of a 60-year-old male who was brought dead to our institute with previous records of a contrast-enhanced CT scan of the brain and MRI with evidence of tumor in the maxillary sinus with intracranial extensions. The histopathological examination of the mass in the maxillary sinus proved to be SNUC with metastases to the brain, lungs, and around the aorta. These tumors are undifferentiated and are distinct from other poorly differentiated tumors in deriving their origin from the Schneiderian epithelium. The aggressive nature of the tumor renders the prognosis quite dismal. SNUCs need to be early recognized and distinguished from other poorly differentiated carcinomas with the help of immunohistochemistry. Competing Interests: Conflict of interest: None. (Copyright: © 2020 The Authors.)
Databáze:	MEDLINE
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