Clinical features and treatment outcomes of endogenous Klebsiella endophthalmitis: a 12-year review.

Autor:	Mak CY; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, New Territories, Hong Kong, China.; Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, New Territories, Hong Kong, China., Ho M; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, New Territories, Hong Kong, China.; Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, New Territories, Hong Kong, China., Iu LP; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, New Territories, Hong Kong, China.; Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, New Territories, Hong Kong, China., Sin HP; Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, New Territories, Hong Kong, China., Chen LJ; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, New Territories, Hong Kong, China.; Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, New Territories, Hong Kong, China., Lui G; Division of Infectious Diseases, Department of Medicine and Therapeutics, the Chinese University of Hong Kong, New Territories, Hong Kong, China., Brelen ME; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, New Territories, Hong Kong, China.; Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, New Territories, Hong Kong, China., Young AL; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, New Territories, Hong Kong, China.; Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, New Territories, Hong Kong, China.
Jazyk:	angličtina
Zdroj:	International journal of ophthalmology [Int J Ophthalmol] 2020 Dec 18; Vol. 13 (12), pp. 1933-1940. Date of Electronic Publication: 2020 Dec 18 (Print Publication: 2020).
DOI:	10.18240/ijo.2020.12.14
Abstrakt:	Aim: To identify the clinical features and treatment outcomes of endogenous Klebsiella pneumoniae endophthalmitis and investigate prognostic factors of poor visual outcome. Methods: The clinical records of all patients diagnosed with endogenous Klebsiella endophthalmitis between January 2007 to December 2018 in Prince of Wales Hospital, Hong Kong, China were retrospectively reviewed. Thorough ophthalmological examination findings were recorded in the case note, including visual acuity testing, slit-lamp examination, indirect ophthalmoscopy and B-scan ultrasonography if media opacity precluded fundus viewing. Results: A total of 18 eyes in 14 patients were identified. Bilateral involvement was noted in 4 patients (28.6%). Hepatobiliary sepsis was the source in 9 patients (64.3%). Culture of intraocular fluid was positive in 5 out of 18 eyes (27.8%). Mortality was noted in 2 patients (14.3%). Mean final visual acuity was 20/1500. Six out of 16 eyes had total loss of sight (37.5%) and 3 eyes required evisceration (18.8%). Multivariate linear regression revealed poor presenting visual acuity ( P =0.031) and lack of fundus view due to vitritis ( P =0.02) as prognostic factors of poor visual outcome. Conclusion: Visual outcome of endogenous Klebsiella endophthalmitis is poor. Poor presenting visual acuity and lack of fundus view predict poor visual outcome. High index of suspicion for endophthalmitis is important in Klebsiella sepsis patients with complaints of ocular symptoms. Ophthalmological screening is recommended in non-communicable patients with Klebsiella sepsis. (International Journal of Ophthalmology Press.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu