An audit of brain tumor patients treated in 5 years at a single institute: Our regional cancer center experience.

Autor: Patel PN; Department of Radiotherapy, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India., Bhattacharya J; Department of Radiotherapy, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India., Vyas RK; Department of Radiotherapy, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India., Suryanarayana U; Department of Radiotherapy, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India.
Jazyk: angličtina
Zdroj: Journal of cancer research and therapeutics [J Cancer Res Ther] 2020 Oct-Dec; Vol. 16 (6), pp. 1466-1469.
DOI: 10.4103/jcrt.JCRT_202_18
Abstrakt: Introduction: Brain tumors constitute a small presentation of all cancers (1.4%) and cancer related deaths (2.5%). Most of the brain tumors are malignant and carry bad prognosis and even if those which are benign still can interfere with brain functions that are required for daily living. We did an audit of brain tumor patients treated in our center and see their prognosis in correlation with different histological types.
Materials and Methods: We analyzed 497 patients treated at our center from June 2007 to June 2012 of different histological types. All the patients underwent complete central nervous system examination and thorough workup including hematological investigations, radiological investigations, and confirmation of histological type by biopsy. These patients were then treated with surgery followed by radiotherapy or upfront curative radiotherapy as per staging and then kept on regular follow-up as per institutional protocol.
Results: Majority of patients were astrocytomas (309 patients) followed by a pituitary adenoma (39 patients), oligodendroglioma (33 patients), medulloblastoma (22 patients), arteriovenous malformations (19 patients), craniopharyngioma (16 patients), and recurrent brain tumors (12 patients). There were few cases of central nervous lymphoma, meningioma, melanocytoma, ependymomas, schwannomas, hemangiopericytoma, gliosarcoma, and primitive neuroectodermal tumor. The histological types vary differently regarding presentation, treatment, and prognosis.
Conclusion: Astrocytomas are the most common tumors in presentation (309 patients) in which the high-grade astrocytomas carried worse prognosis. Benign tumors such as pituitary adenomas, schwannomas, and craniopharyngiomas had the best prognosis with survival seen up to almost last follow-up.
Competing Interests: None
Databáze: MEDLINE
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