Genomic signatures of recombination in a natural population of the bdelloid rotifer Adineta vaga.

Autor: Vakhrusheva OA; Skolkovo Institute of Science and Technology, Moscow, 121205, Russian Federation. O.Vakhrusheva@skoltech.ru., Mnatsakanova EA; Department of General Ecology and Hydrobiology, Faculty of Biology, M. V. Lomonosov Moscow State University, Moscow, 119234, Russian Federation., Galimov YR; Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, 119334, Russian Federation., Neretina TV; Faculty of Biology, M. V. Lomonosov Moscow State University, Moscow, 119234, Russian Federation.; Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow, 127051, Russian Federation.; A. N. Belozersky Institute of Physico-Chemical Biology, M. V. Lomonosov Moscow State University, Moscow, 119992, Russian Federation., Gerasimov ES; Faculty of Biology, M. V. Lomonosov Moscow State University, Moscow, 119234, Russian Federation.; Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow, 127051, Russian Federation.; Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, Sechenov University, Moscow, 119435, Russian Federation., Naumenko SA; Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow, 127051, Russian Federation.; Department of Biostatistics, Harvard Chan School of Public Health, Boston, MA, 02115, USA., Ozerova SG; Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, 119334, Russian Federation.; Medkvadrat, Moscow, 115409, Russian Federation., Zalevsky AO; Faculty of Bioengineering and Bioinformatics, M. V. Lomonosov Moscow State University, Moscow, 119234, Russian Federation.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow, 117997, Russian Federation., Yushenova IA; Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, MA, 02543, USA., Rodriguez F; Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, MA, 02543, USA., Arkhipova IR; Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, MA, 02543, USA., Penin AA; Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow, 127051, Russian Federation., Logacheva MD; Skolkovo Institute of Science and Technology, Moscow, 121205, Russian Federation.; Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow, 127051, Russian Federation.; A. N. Belozersky Institute of Physico-Chemical Biology, M. V. Lomonosov Moscow State University, Moscow, 119992, Russian Federation., Bazykin GA; Skolkovo Institute of Science and Technology, Moscow, 121205, Russian Federation.; Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow, 127051, Russian Federation., Kondrashov AS; A. N. Belozersky Institute of Physico-Chemical Biology, M. V. Lomonosov Moscow State University, Moscow, 119992, Russian Federation.; Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Jazyk: angličtina
Zdroj: Nature communications [Nat Commun] 2020 Dec 18; Vol. 11 (1), pp. 6421. Date of Electronic Publication: 2020 Dec 18.
DOI: 10.1038/s41467-020-19614-y
Abstrakt: Sexual reproduction is almost ubiquitous among extant eukaryotes. As most asexual lineages are short-lived, abandoning sex is commonly regarded as an evolutionary dead end. Still, putative anciently asexual lineages challenge this view. One of the most striking examples are bdelloid rotifers, microscopic freshwater invertebrates believed to have completely abandoned sexual reproduction tens of Myr ago. Here, we compare whole genomes of 11 wild-caught individuals of the bdelloid rotifer Adineta vaga and present evidence that some patterns in its genetic variation are incompatible with strict clonality and lack of genetic exchange. These patterns include genotype proportions close to Hardy-Weinberg expectations within loci, lack of linkage disequilibrium between distant loci, incongruent haplotype phylogenies across the genome, and evidence for hybridization between divergent lineages. Analysis of triallelic sites independently corroborates these findings. Our results provide evidence for interindividual genetic exchange and recombination in A. vaga, a species previously thought to be anciently asexual.
Databáze: MEDLINE
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