MuscleAtlasExplorer: a web service for studying gene expression in human skeletal muscle.

Autor: Asplund O; Genomics, Diabetes and Endocrinology Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Jan Waldenströms gata 35, Malmö 20502, Sweden., Rung J; SciLifeLab, BMC, Husargatan 3, Uppsala University, Uppsala 751 22, Sweden., Groop L; Genomics, Diabetes and Endocrinology Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Jan Waldenströms gata 35, Malmö 20502, Sweden.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Tukholmankatu 800290 Helsinki, Finland., Prasad B R; Genomics, Diabetes and Endocrinology Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Jan Waldenströms gata 35, Malmö 20502, Sweden., Hansson O; Genomics, Diabetes and Endocrinology Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Jan Waldenströms gata 35, Malmö 20502, Sweden.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Tukholmankatu 800290 Helsinki, Finland.
Jazyk: angličtina
Zdroj: Database : the journal of biological databases and curation [Database (Oxford)] 2020 Dec 18; Vol. 2020.
DOI: 10.1093/database/baaa111
Abstrakt: MuscleAtlasExplorer is a freely available web application that allows for the exploration of gene expression data from human skeletal muscle. It draws from an extensive publicly available dataset of 1654 skeletal muscle expression microarray samples. Detailed, manually curated, patient phenotype data, with information such as age, sex, BMI and disease status, are combined with skeletal muscle gene expression to provide insights into gene function in skeletal muscle. It aims to facilitate easy exploration of the data using powerful data visualization functions, while allowing for sample selection, in-depth inspection and further analysis using external tools. Availability: MuscleAtlasExplorer is available at https://mae.crc.med.lu.se/mae2 (username 'muscle' and password 'explorer' pre-publication).
(© The Author(s) 2020. Published by Oxford University Press.)
Databáze: MEDLINE
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