Regional differences in perceived treatments needs and priorities in relation to antiretroviral therapy among people living with HIV in 25 countries.

Autor: Okoli C; ViiV Healthcare, Brentford, Middlesex, United Kingdom. Electronic address: chinyere.x.okoli@viivhealthcare.com., Van de Velde N; ViiV Healthcare, Brentford, Middlesex, United Kingdom., Allan B; International Council of AIDS Service Organizations (ICASO), Toronto, Canada., Hardy WD; Division of Infectious Diseases, Johns Hopkins University School of Medicine, MD, USA., Corbelli GM; European AIDS Treatment Group, Rome, Lazio, Italy., Muchenje M; ViiV Healthcare, Canada., Castellanos E; Global Action for Trans* Equality (GATE), Belize., Brough G; Positively UK, 345 City Road, London EC1V 1LR, United Kingdom., Young B; ViiV Healthcare, Research Triangle Park, NC, USA., Eremin A; AIDS Center Foundation, Moscow, Russia., Ramothwala P; Positive Convention Network, South Africa., McBritton M; Barong Cultural Institute, Brazil., de Los Rios P; ViiV Healthcare, Research Triangle Park, NC, USA.
Jazyk: angličtina
Zdroj: Preventive medicine [Prev Med] 2021 Jan; Vol. 142, pp. 106372. Date of Electronic Publication: 2020 Dec 24.
DOI: 10.1016/j.ypmed.2020.106372
Abstrakt: While geographic differences in HIV burden are well documented, less is known about regional differences in perceived treatment needs. To fill this gap, the 2019 Positive Perspectives study of people living with HIV (PLHIV) was conducted in 25 countries across Northern America, Latin America, the Asian region, Europe (EU/Schengen countries), Russia, Australia, and South Africa (n = 2389). Overall mean duration of HIV was 10.1 (SD = 9.6) years. The perception that HIV had a negative impact on day-to-day life was lowest among participants from South Africa (14.0%[25/179]) and highest among participants from the Asian region (55.2%[127/230]). Most of the regional gap in the perception that HIV had a negative impact on daily life was explained by regional differences in medication-related unmet needs, stigma, demographic factors, and comorbidities. The percentage who felt they understood their treatment was highest among participants from Australia (87.5%[105/120]) and lowest among those from Russia (62.0%[93/150]), the Asian region (62.2%[143/230]), and South Africa (62.6%[112/179]). Among participants from Northern America, Europe, and Latin America, the treatment goals with the largest absolute increase in perceived importance, from time of starting treatment to time of survey among those diagnosed for ≥1 year, were minimizing the long term impact of antiretroviral treatment and keeping the number of medicines in their antiretroviral regimen at a minimum. Tailored approaches to care of PLHIV are needed as different regions have different disease burden and treatment needs. Equitable approaches to HIV care are needed across and within regions to ensure that patients' unmet needs and preferences are addressed to improve their overall wellbeing and health-related quality of life.
(Copyright © 2020 The Author(s). Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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