Expert Consensus Guidelines on Minimally Invasive Donor Hepatectomy for Living Donor Liver Transplantation From Innovation to Implementation: A Joint Initiative From the International Laparoscopic Liver Society (ILLS) and the Asian-Pacific Hepato-Pancreato-Biliary Association (A-PHPBA).

Autor: Cherqui D; AP-HP, Hepatobiliary Center, Paul Brousse Hospital, Université Paris Saclay, Villejuif, France., Ciria R; Unit of Hepatobiliary Surgery and Liver Transplantation. University Hospital Reina Sofía, Cordoba, Spain., Kwon CHD; Department of General Surgery, Digestive Disease & Surgery Institute, Lerner College of Medicine, Cleveland Clinic, Cleveland, Ohio.; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Kim KH; Division of Liver Transplantation and Hepatobiliary Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Broering D; Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Al Faisal University, Riyadh, KSA., Wakabayashi G; Center for Advanced Treatment of Hepatobiliary and Pancreatic Diseases, Ageo Central General Hospital, Ageo, Japan., Samstein B; Department of Surgery, Division of Liver Transplantation and Hepatobiliary Surgery, Weill Cornell Medical College, New York, New York., Troisi RI; Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Al Faisal University, Riyadh, KSA.; Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy; Department of Human Structure and Repair, Ghent University, Belgium., Han HS; Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea., Rotellar F; Department of General Surgery, Clínica Universidad de Navarra, School of Medicine, University of Navarra, Pamplona, Spain., Soubrane O; Department of Hepatopancreatobiliary Surgery and Liver Transplantation, Beaujon Hospital, Assistance Publique Hôpitaux de Paris and Université de Paris, Clichy, France., Briceño J; Unit of Hepatobiliary Surgery and Liver Transplantation. University Hospital Reina Sofía, Cordoba, Spain., Alconchel F; Department of Surgery, Virgen de la Arrixaca University Hospital, Murcia, Spain; Instituto Murciano de Investigación Biosanitaria (IMIB-Arrixaca), Murcia, Spain., Ayllón MD; Unit of Hepatobiliary Surgery and Liver Transplantation. University Hospital Reina Sofía, Cordoba, Spain., Berardi G; Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy; Department of Human Structure and Repair, Ghent University, Belgium., Cauchy F; Department of Hepatopancreatobiliary Surgery and Liver Transplantation, Beaujon Hospital, Assistance Publique Hôpitaux de Paris and Université de Paris, Clichy, France., Luque IG; Unit of Hepatobiliary Surgery and Liver Transplantation. University Hospital Reina Sofía, Cordoba, Spain., Hong SK; Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea., Yoon YY; Division of Liver Transplantation and Hepatobiliary Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Egawa H; Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University., Lerut J; Institut de Recherche Expérimentale et Clinique Université Catholique de Louvain Brussels, Belgium., Lo CM; Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China., Rela M; The Institute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Center, Bharat Institute of Higher Education and Research, Chennai, India.; Institute of Liver Studies, King's College Hospital, London, UK., Sapisochin G; Multi-Organ Transplant and HPB Surgical Oncology, Division of General Surgery, University Health Network, Department of Surgery, University of Toronto, Canada., Suh KS; Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea.
Jazyk: angličtina
Zdroj: Annals of surgery [Ann Surg] 2021 Jan 01; Vol. 273 (1), pp. 96-108.
DOI: 10.1097/SLA.0000000000004475
Abstrakt: Objective: The Expert Consensus Guidelines initiative on MIDH for LDLT was organized with the goal of safe implementation and development of these complex techniques with donor safety as the main priority.
Background: Following the development of minimally invasive liver surgery, techniques of MIDH were developed with the aim of reducing the short- and long-term consequences of the procedure on liver donors. These techniques, although increasingly performed, lack clinical guidelines.
Methods: A group of 12 international MIDH experts, 1 research coordinator, and 8 junior faculty was assembled. Comprehensive literature search was made and studies classified using the SIGN method. Based on literature review and experts opinions, tentative recommendations were made by experts subgroups and submitted to the whole experts group using on-line Delphi Rounds with the goal of obtaining >90% Consensus. Pre-conference meeting formulated final recommendations that were presented during the plenary conference held in Seoul on September 7, 2019 in front of a Validation Committee composed of LDLT experts not practicing MIDH and an international audience.
Results: Eighteen Clinical Questions were addressed resulting in 44 recommendations. All recommendations reached at least a 90% consensus among experts and were afterward endorsed by the validation committee.
Conclusions: The Expert Consensus on MIDH has produced a set of clinical guidelines based on available evidence and clinical expertise. These guidelines are presented for a safe implementation and development of MIDH in LDLT Centers with the goal of optimizing donor safety, donor care, and recipient outcomes.
Competing Interests: The authors declare no conflicts of interest.
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Databáze: MEDLINE