Therapeutic Implications of COVID-19 for the Interventional Cardiologist.

Autor:	Kelham M; Department of Cardiology, 560754Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom., Choudry FA; Department of Cardiology, 560754Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.; Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, 4617Queen Mary University of London, London, United Kingdom., Hamshere S; Department of Cardiology, 560754Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom., Beirne AM; Department of Cardiology, 560754Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.; Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, 4617Queen Mary University of London, London, United Kingdom., Rathod KS; Department of Cardiology, 560754Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.; Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, 4617Queen Mary University of London, London, United Kingdom., Baumbach A; Department of Cardiology, 560754Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.; Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, 4617Queen Mary University of London, London, United Kingdom., Ahluwalia A; Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, 4617Queen Mary University of London, London, United Kingdom., Mathur A; Department of Cardiology, 560754Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.; Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, 4617Queen Mary University of London, London, United Kingdom., Jones DA; Department of Cardiology, 560754Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.; Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, 4617Queen Mary University of London, London, United Kingdom.
Jazyk:	angličtina
Zdroj:	Journal of cardiovascular pharmacology and therapeutics [J Cardiovasc Pharmacol Ther] 2021 May; Vol. 26 (3), pp. 203-216. Date of Electronic Publication: 2020 Dec 17.
DOI:	10.1177/1074248420982736
Abstrakt:	Although COVID-19 is viewed primarily as a respiratory disease, cardiovascular risk factors and disease are prevalent among infected patients and are associated with worse outcomes. In addition, among multiple extra-pulmonary manifestations, there has been an increasing recognition of specific cardiovascular complications of COVID-19. Despite this, in the initial stages of the pandemic there was evidence of a reduction in patients presenting to acute cardiovascular services. In this masterclass review, with the aid of 2 exemplar cases, we will focus on the important therapeutic implications of COVID-19 for interventional cardiologists. We summarize the existing evidence base regarding the varied cardiovascular presentations seen in COVID-19 positive patients and the prognostic importance and potential mechanisms of acute myocardial injury in this setting. Importantly, through the use of a systematic review of the literature, we focus our discussion on the observed higher rates of coronary thrombus burden in patients with COVID-19 and acute coronary syndromes.
Databáze:	MEDLINE
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