High-sugar feeding and increasing cholesterol levels in infants.

Autor:	Zubin Maslov P; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hill JA; UT Southwestern Medical Centre, Dallas, TX, USA., Lüscher TF; Royal Brompton & Harefield Hospitals, Imperial College London, London, UK.; Centre for Molecular Cardiology, University of Zurich, Zurich, Switzerland., Narula J; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jazyk:	angličtina
Zdroj:	European heart journal [Eur Heart J] 2021 Mar 21; Vol. 42 (12), pp. 1132-1135.
DOI:	10.1093/eurheartj/ehaa868
Abstrakt:	Hypercholesterolaemia is an important risk factor for cardiovascular disease. Both total and LDL cholesterol levels are three-fold higher at the end of the first year of life and about four-fold higher in adulthood compared with the neonatal period. In the USA, only 25% of infants are exclusively breastfed and simple carbohydrate-rich formulas are preferentially consumed. Spikes in fasting glucose and insulin have been reported in formula-fed infants and are associated with higher levels of proprotein convertase subtilisin/kexin type 9, suggesting a potential link between high simple sugar intake and consequent increase in LDL cholesterol in early childhood. (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: journals.permissions@oup.com.)
Databáze:	MEDLINE
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