Mechanisms of Colonization Resistance Against Clostridioides difficile.

Autor: Pike CM; Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA., Theriot CM; Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
Jazyk: angličtina
Zdroj: The Journal of infectious diseases [J Infect Dis] 2021 Jun 16; Vol. 223 (12 Suppl 2), pp. S194-S200.
DOI: 10.1093/infdis/jiaa408
Abstrakt: Clostridioides difficile is an urgent antimicrobial-resistant bacterium, causing mild to moderate and sometimes life-threatening disease. Commensal gut microbes are critical for providing colonization resistance against C difficile and can be leveraged as non-antibiotic alternative therapeutics for the prevention and treatment of C difficile infection.
(© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.)
Databáze: MEDLINE