(Immuno)histological Analysis of Ewing Sarcoma.

Autor: Marcilla D; Institute of Biomedicine of Sevilla (IBiS), Virgen del Rocio University Hospital/CSIC/University of Sevilla/CIBERONC, Seville, Spain., Machado I; Pathology Department, Instituto Valenciano de Oncología, Valencia, Spain.; Pathology Department, Patologika Hospital Quirón Valencia, Valencia, Spain., Grünewald TGP; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany., Llombart-Bosch A; Department of Pathology, University of Valencia, Valencia, Spain., de Álava E; Institute of Biomedicine of Sevilla (IBiS), Virgen del Rocio University Hospital/CSIC/University of Sevilla/CIBERONC, Seville, Spain. enrique.alava.sspa@juntadeandalucia.es.; Department of Normal and Pathological Cytology and Histology, School of Medicine, University of Seville, Seville, Spain. enrique.alava.sspa@juntadeandalucia.es.
Jazyk: angličtina
Zdroj: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2226, pp. 49-64.
DOI: 10.1007/978-1-0716-1020-6_5
Abstrakt: The diagnosis of Ewing sarcoma requires the integration of the information generated from numerous techniques, some of them being very sophisticated. However, the first steps of the diagnostic process are crucial to achieve the maximum possible diagnostic performance. In this chapter we will review how to handle the diagnostic specimen from its collection, how to prepare it for diagnosis, how to make a complete pathology report, and provide guidance for the reasonable use of immunohistochemical techniques in this malignancy.
Databáze: MEDLINE